Human Pentosidine ELISA Kit

Human Pentosidine ELISA Kit

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文獻引用 (10) 說明書下載

中文名稱：

人戊糖素(Pentosidine)酶聯免疫試劑盒
貨號：

CSB-E09415h
規格：

96T/48T
價格：

￥3200/￥2500
其他：

CUSABIO Wins 2024 Bioz Rapid Star? Award in the ELISA category

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產品描述：

人戊糖素(Pentosidine)酶聯免疫試劑盒（CSB-E09415h）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿、尿液樣本中的Pentosidine含量。Pentosidine是一個靶點，它屬于晚期糖基化終末產物（AGEs）。在體內，它主要通過美拉德反應形成并逐漸積累。研究機制方面，它與糖尿病并發癥、衰老等密切相關，可引發氧化應激和炎癥反應，常作為評估相關疾病風險和進程的生物標志物。試劑盒檢測范圍為31.25 pmol/mL-2000 pmol/mL，該產品適用于基礎醫學研究、疾病機制探索、藥物干預效果評估等科研場景，為代謝性疾病、衰老相關疾病及骨關節健康研究提供可靠的生物標志物檢測方案。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
縮寫：

Pentosidine
種屬：

Homo sapiens (Human)
樣本類型：

serum, plasma, tissue homogenates, urine
檢測范圍：

31.25 pmol/mL-2000 pmol/mL
靈敏度：

7.81 pmol/mL
反應時間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領域：

Others
測定原理：

quantitative
測定方法：

Sandwich

精密度：

線性度：

To assess the linearity of the assay, samples were spiked with high concentrations of human Pentosidine in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
	Sample	Serum(n=4)
1:1	Average %	94
	Range %	81-102
1:2	Average %	95
	Range %	84-105
1:4	Average %	104
	Range %	91-111
1:8	Average %	95
	Range %	80-103

回收率：

The recovery of human Pentosidine spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.

Sample Type	Average % Recovery	Range
Serum (n=5)	92	85-105
EDTA plasma (n=4)	94	88-105

標準曲線：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

pmol/ml	OD1	OD2	Average	Corrected
2000	2.677	2.697	2.687	2.537
1000	1.843	1.864	1.854	1.704
500	1.163	1.153	1.158	1.008
250	0.742	0.754	0.748	0.598
125	0.447	0.461	0.454	0.304
62.5	0.347	0.359	0.353	0.203
31.25	0.268	0.262	0.265	0.115
0	0.154	0.146	0.150

數據處理：

ELISA操作視頻及標曲繪制軟件下載
貨期：

3-5 working days

Serum Pentosidine in Relation to Obesity in Patients with Type 2 Diabetes and Healthy Controls S Baumann, L Sewing, C Traechslin,Calcified Tissue International,2025
Serum Advanced Glycation End Products and Their Soluble Receptor as New Biomarkers in Systemic Lupus Erythematosus I Carrión,Biomedicines,2024
Effect of Vitamin D Receptor Activation on the AGE/RAGE System and Myeloperoxidase in Chronic Kidney Disease Patients Torino C,Oxidative medicine and cellular longevity,2023
The Burden of Impaired Serum Albumin Antioxidant Properties and Glyco-Oxidation in Coronary Heart Disease Patients with and without Type 2 Diabetes Mellitus F Piarulli,Antioxidants,2022
BONE HISTOMORPHOMETRY IN YOUNG PATIENTS WITH TYPE 2 DIABETES IS AFFECTED BY DISEASE CONTROL AND CHRONIC COMPLICATIONS Andrade V F C, et al,The Journal of Clinical Endocrinology & Metabolism,2019
A next generation setup for pre-fractionation of non-denatured proteins reveals diverse albumin proteoforms each carrying several post-translational modifications Rhode H, et al,Scientific Reports,2019
Increased level of advanced glycation end-products in renal transplant patients is associated with decreased measured GFR and grafted kidney function. Shahbazian, et al,Journal of Nephropathology,2019
The effects of n-3 long-chain polyunsaturated fatty acid supplementation on AGEs and sRAGE in type 2 diabetes mellitus Kurt A.et al,J Physiol Biochem.,2016
Effects of ginger on serum glucose, advanced glycation end products, and inflammation in peritoneal dialysis patients Imani H.et al,Nutrition.,2015
Pomegranate (Punicagranatum) juice decreases lipid peroxidation, but has no effect on plasma advanced glycated end-products in adults with type 2 Sohrab G. et al,Food Nutr Res,2015

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Intra-assay Precision (Precision within an assay): CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<10%

Three samples of known concentration were tested in twenty assays to assess.