SLC39A6
SLC39A6 (Solute Carrier Family 39 Member 6)是一種轉(zhuǎn)運蛋白，負(fù)責(zé)將錳、鐵和鋅等離子從細(xì)胞外膜運輸?shù)郊?xì)胞內(nèi)。它在人體中廣泛表達，尤其在腦組織中表達水平較高。SLC39A6參與許多生理和病理過程，包括神經(jīng)發(fā)育、免疫調(diào)節(jié)、細(xì)胞凋亡和代謝調(diào)節(jié)等。 近年來的研究發(fā)現(xiàn)，SLC39A6在某些癌癥中的表達水平異常，如乳腺癌、結(jié)腸癌、胃癌和前列腺癌等。SLC39A6的過度表達被認(rèn)為與某些癌癥的發(fā)生和發(fā)展有關(guān)，如通過促進癌細(xì)胞增殖和轉(zhuǎn)移。因此，SLC39A6成為了一個重要的癌癥靶點，可以通過調(diào)節(jié)SLC39A6的表達和活性，以開發(fā)新的治療癌癥的策略。此外，SLC39A6也被認(rèn)為是神經(jīng)退行性疾病的潛在治療靶點。
更多SLC39A6相關(guān)閱讀：鋅離子轉(zhuǎn)運蛋白，抗體偶聯(lián)藥物ADC新晉靶點！
熱銷產(chǎn)品
Recombinant Human SLC39A6, partial (Active) (CSB-BP621669HU1)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human SLC39A6 at 1 μg/ml can bind Anti-SLC39A6 recombinant antibody (CSB-RA621669MA1HU), the EC50 is 0.6873-0.9010 ng/mL.
● SLC39A6 Recombinant Monoclonal Antibody CSB-RA621669MA1HU
驗證數(shù)據(jù)
The Binding Activity of SLC39A6 with anti-SLC39A6 antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human SLC39A6(CSB-BP621669HU) at 1 μg/ml can bind Anti-SLC39A6-1 recombinant antibody, the EC50 is 0.6873-0.9010 ng/mL.
SLC39A6 Antibodies
SLC39A6 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA021635GA01HU | SLC39A6 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA621669DSR1HU | SLC39A6 Antibody | Human | ELISA, IHC |
| CSB-PA621669DSR2HU | SLC39A6 Antibody | Human | ELISA, WB, IHC |
| CSB-PA559833 | SLC39A6 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA933661 | SLC39A6 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-RA621669MA1HU | SLC39A6 monoclonal antibody | Human, Macaca fascicularis | ELISA |
SLC39A6 Proteins
SLC39A6 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP621669HU1 CSB-EP621669HU1 CSB-MP621669HU1 CSB-EP621669HU1-B |
Recombinant Human Zinc transporter ZIP6 (SLC39A6), partial | Yeast E.coli Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF621669HU | Recombinant Human Zinc transporter ZIP6 (SLC39A6) | in vitro E.coli expression system |
| CSB-BP621669HU1 | Recombinant Human Zinc transporter ZIP6 (SLC39A6), partial (Active) | Baculovirus |
SLC39A6 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP687169RA1 CSB-EP687169RA1 CSB-MP687169RA1 CSB-EP687169RA1-B |
Recombinant Rat Zinc transporter ZIP6 (Slc39a6), partial | Yeast E.coli Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF687169RA | Recombinant Rat Zinc transporter ZIP6 (Slc39a6) | in vitro E.coli expression system |
SLC39A6 Proteins for Pongo abelii (Sumatran orangutan)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP735748PYX1 CSB-EP735748PYX1 CSB-BP735748PYX1 CSB-MP735748PYX1 CSB-EP735748PYX1-B |
Recombinant Pongo abelii Zinc transporter ZIP6 (SLC39A6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF735748PYX | Recombinant Pongo abelii Zinc transporter ZIP6 (SLC39A6) | in vitro E.coli expression system |
SLC39A6 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP804901MO1 CSB-EP804901MO1 CSB-BP804901MO1 CSB-MP804901MO1 CSB-EP804901MO1-B |
Recombinant Mouse Zinc transporter ZIP6 (Slc39a6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF804901MO | Recombinant Mouse Zinc transporter ZIP6 (Slc39a6) | in vitro E.coli expression system |
