S100A8

S100A8，全稱為鈣結(jié)合蛋白S100A8，是一種重要的多功能蛋白，屬于S100蛋白家族。該蛋白家族廣泛存在于人體組織中，參與多種生理和病理過程。S100A8蛋白也被稱為鈣衛(wèi)蛋白A或L1輕鏈抗原，在炎癥和免疫反應(yīng)中發(fā)揮著關(guān)鍵作用。它通常與S100A9蛋白形成異二聚體，即鈣衛(wèi)蛋白，參與細(xì)胞骨架重排、花生四烯酸代謝等過程。S100A8蛋白的表達(dá)水平在炎癥反應(yīng)中會顯著升高，并與多種炎癥性疾病密切相關(guān)，如類風(fēng)濕性關(guān)節(jié)炎、炎癥性腸病、系統(tǒng)性紅斑狼瘡和銀屑病等。此外，S100A8蛋白還與某些癌癥的發(fā)生發(fā)展有關(guān)，如腎細(xì)胞癌、黑色素瘤和乳腺癌等。目前，針對S100A8蛋白的藥物研發(fā)主要集中在抗炎和抗癌領(lǐng)域。例如，有研究開發(fā)出S100A8/A9蛋白抑制劑，如Tepotinib和Unc0631，用于治療炎癥性疾病和癌癥。此外，還有研究探索S100A8蛋白在炎癥和癌癥中的作用機(jī)制，以期為開發(fā)新的治療藥物提供更多線索。

熱銷產(chǎn)品

S100A8 Monoclonal Antibody (CSB-MA0206411A0m)

驗(yàn)證數(shù)據(jù)

Immunohistochemical of paraffin-embedded human cervical cancer using CSB-MA0206411A0m at dilution of 1:200

Immunohistochemical of paraffin-embedded human spleen using CSB-MA0206411A0m at dilution of 1:200

Human S100 calcium binding protein A8/calgranulin A,S100A8 ELISA Kit (CSB-E11833h)

驗(yàn)證數(shù)據(jù)

貨號：CSB-E11833h

規(guī)格：96T/48T

靈敏度：0.31 ng/mL

檢測范圍：1.25 ng/mL-80 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

S100A8 Antibody

S100A8 Protein

S100A8 ELISA Kit

S100A8 Antibodies

S100A8 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA020641HA01HU	S100A8 Antibody	Human	ELISA, IHC
CSB-PA020641HB01HU	S100A8 Antibody, HRP conjugated	Human	ELISA
CSB-PA020641HD01HU	S100A8 Antibody, Biotin conjugated	Human	ELISA
CSB-MA0206411A0m	S100A8 Monoclonal Antibody	Human	ELISA,IHC
CSB-PA020641GA01HU	S100A8 Antibody	Human,Mouse,Rat	ELISA,WB,IHC

S100A8 for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA020641DA01MO	S100a8 Antibody	Mouse	ELISA, WB
CSB-PA020641DC01MO	S100a8 Antibody, FITC conjugated	Mouse
CSB-PA020641DD01MO	S100a8 Antibody, Biotin conjugated	Mouse	ELISA
CSB-PA020641HA01MO	S100a8 Antibody	Mouse	ELISA

S100A8 for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA020641LA01RA	S100a8 Antibody	Rat	ELISA, WB
CSB-PA020641LD01RA	S100a8 Antibody, Biotin conjugated	Rat	ELISA

S100A8 Proteins

S100A8 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP020641MO	Recombinant Mouse Protein S100-A8 (S100a8)	Yeast
CSB-EP020641MO	Recombinant Mouse Protein S100-A8 (S100a8)	E.coli
CSB-BP020641MO CSB-MP020641MO CSB-EP020641MO-B	Recombinant Mouse Protein S100-A8 (S100a8)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP020641MOe0	Recombinant Mouse Protein S100-A8 (S100a8)	E.coli

S100A8 Proteins for Bos taurus (Bovine)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP020641BO CSB-EP020641BO CSB-BP020641BO CSB-MP020641BO CSB-EP020641BO-B	Recombinant Bovine Protein S100-A8 (S100A8)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

S100A8 Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP020641RA	Recombinant Rat Protein S100-A8 (S100a8)	Yeast
CSB-EP020641RA	Recombinant Rat Protein S100-A8 (S100a8)	E.coli
CSB-BP020641RA CSB-MP020641RA CSB-EP020641RA-B	Recombinant Rat Protein S100-A8 (S100a8)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

S100A8 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP020641HU CSB-EP020641HU CSB-BP020641HU CSB-MP020641HU CSB-EP020641HU-B	Recombinant Human Protein S100-A8 (S100A8)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli