GDF11
GDF11，即生長分化因子11，別名VHO、BMP11、BMP-11，是一種由人類基因編碼的分泌型蛋白，屬于轉(zhuǎn)化生長因子β（TGF-β）超家族成員之一。GDF11可結(jié)合TGF-β受體，導(dǎo)致SMAD家族轉(zhuǎn)錄因子的募集和激活，從而調(diào)節(jié)基因表達(dá)。GDF11在神經(jīng)和其他器官系統(tǒng)的發(fā)育中發(fā)揮作用，并可能調(diào)節(jié)衰老過程。
GDF11目前的研究主要集中于衰老過程以及衰老相關(guān)的疾病，包括促進(jìn)心肌細(xì)胞增殖、神經(jīng)元再生以及造血干細(xì)胞的增殖和功能。GDF11的廣泛生物學(xué)效應(yīng)可能包括逆轉(zhuǎn)衰老過程中的細(xì)胞衰老、逆轉(zhuǎn)年齡相關(guān)的病理變化以及調(diào)節(jié)損傷后的器官再生。
熱銷產(chǎn)品
Recombinant Human Growth/differentiation factor 11 (GDF11) (CSB-EP009344HU)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP009344HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) GDF11.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP009344HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) GDF11.
驗證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA105485(GDF11 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human lymphoma tissue using CSB-PA105485(GDF11 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
Human Growth/differentiation factor 11(GDF11) ELISA kit (CSB-EL009344HU)
驗證數(shù)據(jù)
貨號：CSB-EL009344HU
規(guī)格：96T/48T
靈敏度：7 pg/mL
檢測范圍：28 pg/mL-1800 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
GDF11 Antibodies
GDF11 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA105485 | GDF11 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA009344LA01HU | GDF11 Antibody | Human | ELISA, IHC |
| CSB-PA009344LB01HU | GDF11 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA009344LC01HU | GDF11 Antibody, FITC conjugated | Human | |
| CSB-PA009344LD01HU | GDF11 Antibody, Biotin conjugated | Human | ELISA |
GDF11 Proteins
GDF11 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009344HU CSB-BP009344HU CSB-MP009344HU CSB-EP009344HU-B |
Recombinant Human Growth/differentiation factor 11 (GDF11) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP009344HU | Recombinant Human Growth/differentiation factor 11 (GDF11) | E.coli |
GDF11 ELISA Kit
GDF11 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL009344HU | Human Growth/differentiation factor 11(GDF11) ELISA kit | serum, plasma, tissue homogenates | 7 pg/mL |
