DTX1
E3 ubiquitin-protein ligase DTX1 is a protein in humans that is encoded by DTX1 gene. Functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, suggesting that it can antagonize NOTCH1.
DTX1 Antibodies
DTX1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA114923 | DTX1 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA447859 | DTX1 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA199144 | DTX1 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA773055LA01HU | DTX1 Antibody | Human | ELISA, IF |
| CSB-PA773055LB01HU | DTX1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA773055LC01HU | DTX1 Antibody, FITC conjugated | Human | |
| CSB-PA773055LD01HU | DTX1 Antibody, Biotin conjugated | Human | ELISA |
DTX1 Proteins
DTX1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP723395MO CSB-EP723395MO CSB-BP723395MO CSB-MP723395MO CSB-EP723395MO-B |
Recombinant Mouse Protein deltex-1 (Dtx1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DTX1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP773055HU CSB-EP773055HU CSB-BP773055HU CSB-MP773055HU CSB-EP773055HU-B |
Recombinant Human Protein deltex-1 (DTX1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DTX1 Proteins for Xenopus laevis (African clawed frog)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP803819XBE CSB-EP803819XBE CSB-BP803819XBE CSB-MP803819XBE CSB-EP803819XBE-B |
Recombinant Xenopus laevis Protein deltex-1 (dtx1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DTX1 Proteins for Arabidopsis thaliana (Mouse-ear cress)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP871072DOA CSB-EP871072DOA CSB-BP871072DOA CSB-MP871072DOA CSB-EP871072DOA-B |
Recombinant Arabidopsis thaliana MATE efflux family protein DTX1 (DTX1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
