CXCL16
CXCL16，全稱為C-X-C motif chemokine 16，也被稱為Small-inducible cytokine B16、SR-PSOX等，是一種多功能蛋白，參與多種炎癥性疾病、動脈粥樣硬化和癌癥的發(fā)生發(fā)展。該蛋白可以在多種細(xì)胞類型中觀察到，以可溶形式和跨膜形式存在。可溶性CXCL16作為趨化劑，引導(dǎo)T細(xì)胞遷移至腫瘤細(xì)胞附近，而跨膜CXCL16則與CXCR6受體結(jié)合，增強(qiáng)免疫突觸，提高T細(xì)胞對腫瘤細(xì)胞的識別和裂解能力。研究表明，CXCL16-CXCR6配對在CAR-T治療實體瘤中具有重要作用，通過基因工程改造T細(xì)胞使其高表達(dá)CXCR6，可以增強(qiáng)T細(xì)胞對腫瘤細(xì)胞的殺傷效果，從而提高治療效果。此外，CXCL16與多種疾病相關(guān)，如腎小球腎炎、肺部疾病、動脈粥樣硬化、冠狀動脈疾病、類風(fēng)濕性關(guān)節(jié)炎等，因此在藥物研發(fā)方面也備受關(guān)注。目前，已有針對CXCL16和CXCR6的抗體藥物和診斷試劑在研發(fā)中，有望為相關(guān)疾病的治療提供新的策略。
熱銷產(chǎn)品
CXCL16 Antibody (CSB-PA964027)
驗證數(shù)據(jù)
Western Blot
Positive WB detected in: A549 whole cell lysate, SY5Y whole cell lysate
All lanes: CXCL16 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 28 kDa
Observed band size: 28 kDa
Human CXC-chemokine ligand 16,CXCL16 ELISA Kit (CSB-E08871h)
驗證數(shù)據(jù)
貨號：CSB-E08871h
規(guī)格：96T/48T
靈敏度：3.603 pg/mL
檢測范圍：46.875 pg/mL-3000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CXCL16 Antibodies
CXCL16 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA006245GA01HU | CXCL16 Antibody | Human | ELISA,WB |
| CSB-PA964027 | CXCL16 Antibody | Human | ELISA, WB |
CXCL16 for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA09337A0Rb | Cxcl16 Antibody | Mouse | ELISA |
CXCL16 Proteins
CXCL16 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-RP093374m | Recombinant Mouse C-X-C motif chemokine 16 (Cxcl16), partial | E.coli |
| CSB-YP805950MO CSB-EP805950MO CSB-BP805950MO CSB-MP805950MO CSB-EP805950MO-B |
Recombinant Mouse C-X-C motif chemokine 16 (Cxcl16), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP001191MO | Recombinant Mouse C-X-C motif chemokine 16 protein (Cxcl16), partial (Active) | E.Coli |
CXCL16 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP642801BO CSB-EP642801BO CSB-BP642801BO CSB-MP642801BO CSB-EP642801BO-B |
Recombinant Bovine C-X-C motif chemokine 16 (CXCL16), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCL16 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP721459RA CSB-EP721459RA CSB-BP721459RA CSB-MP721459RA CSB-EP721459RA-B |
Recombinant Rat C-X-C motif chemokine 16 (Cxcl16), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCL16 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP863959HU CSB-EP863959HU CSB-BP863959HU CSB-MP863959HU CSB-EP863959HU-B |
Recombinant Human C-X-C motif chemokine 16 (CXCL16), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCL16 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP875595PI CSB-EP875595PI CSB-BP875595PI CSB-MP875595PI CSB-EP875595PI-B |
Recombinant Pig C-X-C motif chemokine 16 (CXCL16), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCL16 ELISA Kit
CXCL16 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08871h | Human CXC-chemokine ligand 16,CXCL16 ELISA Kit | serum, plasma, tissue homogenates | 3.603 pg/mL |
CXCL16 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08873m | Mouse CXC-chemokine ligand 16,CXCL16 ELISA Kit | serum, plasma,tissue homogenates | 3.012 pg/mL |
