Recombinant Xenopus laevis Runt-related transcription factor 1 (runx1)

中文名稱：

有爪蟾蜍runx1重組蛋白
貨號：

CSB-YP020592XBE
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

有爪蟾蜍runx1重組蛋白
貨號：

CSB-EP020592XBE
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

有爪蟾蜍runx1重組蛋白
貨號：

CSB-EP020592XBE-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

有爪蟾蜍runx1重組蛋白
貨號：

CSB-BP020592XBE
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

有爪蟾蜍runx1重組蛋白
貨號：

CSB-MP020592XBE
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

runx1
Uniprot No.：

Q6PF39
別名：

runx1; aml; cbfa2; Runt-related transcription factor 1; Acute myeloid leukemia 1 protein; XAML; Core-binding factor subunit alpha-2; CBF-alpha-2
種屬：

Xenopus laevis (African clawed frog)
蛋白長度：

full length protein
表達區域：

1-462
氨基酸序列

MRIPVDTSTS RRFTPPSTTL SPGKMSEPIP LNIADSSAAL VGKLRSTDRN MVEVLSDHPG ELVRTDSPNF LCSVLPTHWR CNKTLPIAFK VVALGEVPDG TLVTVMAGND ENYSAELRNA TAAMKSQVAR FNDLRFVGRS GRGKSFTLTI TVFTNPPQVA TYHRAIKITV DGPREPRRHR QKLDEQTKPG NLSFSERLSE LEHFRRTAMR VSPHHPNPMP NPRATLNHSA AFNPQPQGQI QVADTRQVQA SPPWSYDQSY QYLGSIATQS VHPATPISPG RASSMTSLSA ELSSRLSGAS DLTAFSDPRV GIDRQFSTLP SISDPRMHYP GAFTYTPTPV TSGIGIGMSA MTSATRYHTY LPPPYPGSSQ AQSNPFQTSS PSYHLYYGTS AGSYHQFSMM SGGERSPPRI LPPCTNASTG STLLNPNLPN QSDVVEAEGS HSNSPTNMGS TPRLEEAVWR PY
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in primitive hematopoiesis in the embryo.
基因功能參考文獻：
1. Xaml1/Runx1 is required for the specification of Rohon-Beard sensory neurons in Xenopus. PMID: 22173066
2. ETV6-RUNX1 (TEL-AML1) fusion and hyperdiploidy (>50 chromosomes) are favorable genetic features in childhood acute lymphoblastic leukemia (ALL). PMID: 20658612
3. reveal a shift in Runx2 function protein during vertebrate evolution towards its exclusive roles in cartilage hypertrophy and bone differentiation within the amniote lineage PMID: 17474117
亞細胞定位：

Nucleus.
組織特異性：

Shows a complex and dynamic expression pattern. In stage 14-24 embryos, expressed in a subset of neuroblasts in the lateral stripe of the neural plate. In late neurula stages, expression begins in the olfactory placodes. Also expressed in structures that
數據庫鏈接：

KEGG: xla:379657

UniGene: Xl.2874