WDR19 Antibody

中文名稱：

WDR19兔多克隆抗體
貨號：

CSB-PA836733LA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA836733LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA836733LA01HU at dilution of 1:100

Immunofluorescent analysis of A549 cells using CSB-PA836733LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) WDR19 Polyclonal antibody
Uniprot No.：

Q8NEZ3
基因名：

WDR19
別名：

DYF 2 antibody; DYF2 antibody; FLJ23127 antibody; IFT144 antibody; Intraflagellar transport 144 homolog antibody; KIAA1638 antibody; ORF26 antibody; Oseg6 antibody; PWDMP antibody; WD repeat containing protein 19 antibody; WD repeat domain 19 antibody; WD repeat membrane protein PWDMP antibody; WD repeat-containing protein 19 antibody; Wdr19 antibody; WDR19_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human WD repeat-containing protein 19 protein (45-226AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，WDR19 Antibody (CSB-PA836733LA01HU)，的標記方式是Non-conjugated。對于WDR19 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA836733LB01HU	WDR19 Antibody, HRP conjugated	ELISA
FITC	CSB-PA836733LC01HU	WDR19 Antibody, FITC conjugated
Biotin	CSB-PA836733LD01HU	WDR19 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

As component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in cilia function and/or assembly. Essential for functional IFT-A assembly and ciliary entry of GPCRs. Associates with the BBSome complex to mediate ciliary transport.
基因功能參考文獻：
1. Case Reports: that WDR19 mutations can cause dysplastic kidney in addition to nephronophthisis in infants with Sensenbrenner syndrome. PMID: 28621010
2. Nephronophthisis 13 (Autosomal Recessive Polycystic Kidney Disease) is associated with mutations in the WDR19 gene.Caroli disease is a major extra-renal phenotype associated with mutations in WDR19 in the Korean population. PMID: 25726036
3. WDR19 mutations can cause a broad spectrum of ciliopathies that extends to Jeune and Sensenbrenner syndromes, RP and renal NPHP-like phenotypes PMID: 24504730
4. Mutations in WDR19 gene is associated with Caroli disease. PMID: 23559409
5. WDR19: an ancient, retrograde, intraflagellar ciliary protein is mutated in autosomal recessive retinitis pigmentosa and in Senior-Loken syndrome. PMID: 23683095
6. Ciliopathies with skeletal anomalies and renal insufficiency due to mutations in the IFT-A gene WDR19 PMID: 22019273
7. Expressed in normal and neoplastic prostate epithelium and is regulated by androgenic hormones. PMID: 12906858
8. Overexpression of WDR19 is associated with prostate cancer PMID: 18316561
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相關疾?。?/div>
Cranioectodermal dysplasia 4 (CED4); Short-rib thoracic dysplasia 5 with or without polydactyly (SRTD5); Nephronophthisis 13 (NPHP13); Senior-Loken syndrome 8 (SLSN8)
亞細胞定位：

Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium, photoreceptor outer segment.
組織特異性：

Some isoforms are tissue-specific. Highly expressed in the prostate. Lower expression in the cerebellum, pituitary gland, fetal lung, and pancreas. In normal prostate, expressed in both basal and luminal epithelial cells. No expression detected in fibromu
數據庫鏈接：

HGNC: 18340

OMIM: 608151

KEGG: hsa:57728

STRING: 9606.ENSP00000382717

UniGene: Hs.438482

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