UPP2 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) UPP2 Polyclonal antibody
Uniprot No.：

O95045
基因名：

UPP2
別名：

Liver specific uridine phosphorylase antibody; UDRPASE2 antibody; UP2 antibody; UPase 2 antibody; UPASE2 antibody; UPP 2 antibody; UPP2 antibody; UPP2_HUMAN antibody; UrdPase 2 antibody; Uridine phosphorylase 2 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Uridine phosphorylase 2 protein (1-317AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows broad substrate specificity and accepts uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.
基因功能參考文獻：
1. This study demonistrated that use joint test to identified that UPP2 association to Autism Spectrum Disorder. PMID: 21151189
2. A novel structural mechanism for redox regulation of uridine phosphorylase 2 activity PMID: 21855639
3. identification of the novel human uridine phosphorylase, UDPase 2, with broad substrate specificity; UPase-2 gene was mapped to chromosome 2q24.1 and the 2.2-kb mRNA was predominantly expressed in kidney PMID: 12849978
蛋白家族：

PNP/UDP phosphorylase family
組織特異性：

Predominantly expressed in kidney.
數據庫鏈接：

HGNC: 23061

OMIM: 617340

KEGG: hsa:151531

STRING: 9606.ENSP00000387230

UniGene: Hs.128427

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