TEX10 Antibody

說明書

產品詳情

Uniprot No.：

Q9NXF1
基因名：

TEX10
別名：

TEX10 antibody; L18 antibody; Nbla10363 antibody; Testis-expressed protein 10 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human TEX10
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit.
基因功能參考文獻：
1. Tex10 is a core component of the pluripotency network. PMID: 25936917
2. Data suggest that TEX101 is a cancer-related protein and may be useful as a marker for prognosis/diagnosis of and neck squamous cell carcinomas (HNSCC). PMID: 23481573
3. These data define the PELP1-TEX10-WDR18 complex as a regulator of ribosome biogenesis and suggests that its SUMO-controlled distribution coordinates the rate of ribosome formation. PMID: 21326211
亞細胞定位：

Nucleus, nucleoplasm. Cytoplasm. Nucleus, nucleolus.
蛋白家族：

IPI1/TEX10 family
數據庫鏈接：

HGNC: 25988

KEGG: hsa:54881

STRING: 9606.ENSP00000364037

UniGene: Hs.494648

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