SRRM2 Antibody
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中文名稱：SRRM2兔多克隆抗體
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貨號：CSB-PA892369LA01HU
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規格：￥440
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圖片：
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Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA892369LA01HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) SRRM2 Polyclonal antibody
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Uniprot No.：
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基因名：SRRM2
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別名：300 kDa nuclear matrix antigen antibody; CWC21 antibody; KIAA0324 antibody; Ser/Arg-related nuclear matrix protein of 300 kDa antibody; Serine/arginine repetitive matrix protein 2 antibody; Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa antibody; Splicing coactivator subunit SRm300 antibody; SR-related nuclear matrix protein of 300 kDa antibody; SRL300 antibody; SRM300 antibody; SRRM2 antibody; SRRM2_HUMAN antibody; Tax-responsive enhancer element-binding protein 803 antibody; TaxREB803 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Serine/arginine repetitive matrix protein 2 protein (248-462AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，SRRM2 Antibody (CSB-PA892369LA01HU)，的標記方式是Non-conjugated。對于SRRM2 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, IHC
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推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Required for pre-mRNA splicing as component of the spliceosome.
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基因功能參考文獻：
- cellular complexes comprising cactin, DHX8 and SRRM2 sustain precise chromosome segregation, genome stability and cell proliferation by allowing faithful splicing of specific pre-mRNAs. PMID: 28062851
- The S346F mutation in SRRM2 predisposes to papillary thyroid carcinoma by affecting alternative splicing of unidentified downstream target genes. PMID: 26135620
- Data show that the consistent dysregulation of the RNA splicing factor SRRM2 in two different PD neuronal sources and in PD blood makes SRRM2 a strong candidate gene for PD and draws attention to the role of RNA splicing in the disease. PMID: 20161708
- results suggest multiple functions for Cwc21/SRm300 in the splicing process, including an important role in the activation of splicing in association with Isy1. PMID: 19789211
- demonstrate that SRm300, the only serine arginine-related protein known to be at the core of human catalytic spliceosomes, is a functional ortholog of Cwc21p, also interacting directly with Prp8p and Snu114p. PMID: 19854871
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亞細胞定位：Nucleus. Nucleus speckle.
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蛋白家族：CWC21 family
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組織特異性：Expressed in liver, placenta, and white blood cells.
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數據庫鏈接：
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