SQOR Antibody
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中文名稱：SQOR兔多克隆抗體
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貨號：CSB-PA022646ESR2HU
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規格：￥440
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圖片：
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Western blot
All lanes: SQRDL antibody at 4.67μg/ml
Lane 1: A549 whole cell lysate
Lane 2: A431 whole cell lysate
Lane 3: Hela whole cell lysate
Lane 4: HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 50 kDa
Observed band size: 50 kDa -
Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA022646ESR2HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA022646ESR2HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) SQOR Polyclonal antibody
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Uniprot No.：
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基因名：SQOR
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別名：0610039J17Rik antibody; 4930557M22Rik antibody; CGI 44 antibody; CGI44 antibody; mitochondrial antibody; PRO1975 antibody; SQRD_HUMAN antibody; Sqrdl antibody; Sulfide dehydrogenase like antibody; Sulfide quinone reductase like antibody; Sulfide quinone reductase-like (yeast) antibody; Sulfide:quinone oxidoreductase antibody; Sulfide:quinone oxidoreductase, mitochondrial antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Sulfide:quinone oxidoreductase, mitochondrial protein (211-450AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Catalyzes the oxidation of hydrogen sulfide with the help of a quinone, such as ubiquinone-10, giving rise to thiosulfate and ultimately to sulfane (molecular sulfur) atoms. Requires an additional electron acceptor; can use sulfite, sulfide or cyanide (in vitro). It is believed the in vivo electron acceptor is glutathione.
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基因功能參考文獻：
- The evidence supported the significant role of SQRDL in the etiology of postmenopausal osteoporosis and suggest that it may be a genetic risk factor for BMD and osteoporosis in Han Chinese postmenopausal women. PMID: 29855663
- Hydrogen Sulfide Oxidation Catalyzed by Human Sulfide Quinone Oxidoreductase PMID: 26318450
- Therefore, this study reveals the reduction in SQR activity as one of the pathomechanisms associated with Coenzyme Q deficiency syndrome. PMID: 27856619
- Data, including data from studies using recombinant SQR immobilized by embedding in nanodiscs, suggest that immobilized SQR exhibits enhanced catalytic performance; pre-steady-state kinetic characterization of immobilized SQR catalytic cycle indicates that glutathione serves as physiologically relevant sulfur acceptor during hydrogen sulfide oxidation. PMID: 28512131
- The I264T SQRDL polymorphism is associaated with osteoporosis in Korean postmenopausal women. PMID: 26258864
- SQR is part of the human mitochondrial hydrogen sulfide oxidation pathway PMID: 25225291
- Sulfide:quinone oxidoreductase catalyzes the first step in hydrogen sulfide metabolism and produces a sulfane sulfur metabolite. PMID: 22852582
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亞細胞定位：Mitochondrion.
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蛋白家族：SQRD family
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數據庫鏈接：
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