SLC17A1 Antibody
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中文名稱：SLC17A1兔多克隆抗體
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貨號：CSB-PA695593
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規(guī)格：￥1100
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圖片：
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Gel: 8%SDS-PAGE, Lysate: 60 μg, Lane 1-2: Human kidney cancer tissue, Human kidney pericarcinous tissue, Primary antibody: CSB-PA695593(SLC17A1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：SLC17A1
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別名：Na(+)/PI cotransporter 1 antibody; Na/Pi-4 antibody; NAP 1 antibody; Napi1 antibody; NPT 1 antibody; Npt1 antibody; NPT1_HUMAN antibody; Renal Na(+)-dependent phosphate cotransporter 1 antibody; Renal sodium-dependent phosphate transport protein 1 antibody; Renal sodium-phosphate transport protein 1 antibody; Slc17a1 antibody; Sodium phosphate transporter antibody; Sodium-dependent phosphate transport protein 1 antibody; Sodium/phosphate cotransporter 1 antibody; Sodium/phosphate type I cotransporter antibody; Solute carrier family 17 (organic anion transporter) member 1 antibody; solute carrier family 17 (sodium phosphate), member 1 antibody; Solute carrier family 17 (vesicular glutamate transporter) member 1 antibody; Solute carrier family 17 member 1 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthetic peptide of Human SLC17A1
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產(chǎn)品提供形式：Liquid
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應用范圍：ELISA,WB
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推薦稀釋比：
Application Recommended Dilution ELISA 1:1000-1:2000 WB 1:200-1:1000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關產(chǎn)品
靶點詳情
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功能：Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Plays a role in urate transport in the kidney.
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基因功能參考文獻：
- A meta-analysis of all gout with Japanese, Caucasian and NZ Polynesian populations revealed that rs2285340 of SLC22A12 and rs1165196 of SLC17A1 showed a significant association but did not reach a genome-wide significance level. PMID: 27899376
- I269T, a common missense variant of NPT1, might have faster conformation changes than NPT1 wild type in terms of the alternating-access model of transporters, and increases renal urate export in humans. PMID: 27906618
- Data suggest that single nucleotide polymorphisms (SNPs) of solute carrier family 17 member 1 (SLC17A1) are potential biomarkers for altered cholesterol homeostasis and hyperhomocysteinaemia in Japanese men. PMID: 26524967
- Data suggest that single nucleotide polymorphisms (SNPs) rs9467596 and rs2096386 of the solute carrier family 17 (sodium phosphate), member 1 protein (SLC17A1) gene may have a correlation between hyperuricemia and alcohol drinking among Uygur patients. PMID: 26663070
- Polymorphisms in GCKR, SLC17A1 and SLC22A12 were associated with phenotype gout in Han Chinese males. PMID: 26290326
- NPT1/SLC17A1 is a renal urate exporter in humans and its common gain-of-function variant decreases the risk of renal underexcretion gout. PMID: 25252215
- NPT1 is responsible for urate excretion under physiological conditions and its impairment is linked with the occurrence of gout. [review] PMID: 23876149
- We observed a clear effect of SLC17A1 genotype on fructose load in Europeans but not Polynesian subgroups. PMID: 23852697
- Renal urate transporter SLC17A1 is the third locus associated with gout at a genome-wide level of significance. PMID: 22541845
- results strongly suggested that NPT1 is a Cl(-)-dependent polyspecific anion exporter involved in urate excretion under physiological conditions PMID: 20566650
- data suggest that SLC17A1 polymorphisms are associated with the development of gout. PMID: 19556210
- structure and promoter activity, molecular cloning PMID: 11704559
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亞細胞定位：Apical cell membrane; Multi-pass membrane protein.
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蛋白家族：Major facilitator superfamily, Sodium/anion cotransporter family
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組織特異性：Expressed in kidney cortex, liver and brain but not in other tissues.
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數(shù)據(jù)庫鏈接：
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