MGC15754 antibody; RAS like estrogen regulated growth inhibitor antibody; Ras related and estrogen regulated growth inhibitor antibody; Ras-related and estrogen-regulated growth inhibitor antibody; Rerg antibody; RERG_HUMAN antibody; Weakly similar to N ras protein [H.sapiens] antibody
宿主:
Rabbit
反應種屬:
Human,Mouse,Rat
免疫原:
Human RERG
免疫原種屬:
Homo sapiens (Human)
抗體亞型:
IgG
純化方式:
Antigen Affinity Purified
濃度:
It differs from different batches. Please contact us to confirm it.
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential.
基因功能參考文獻:
this study shows that miR-382-5p expression is negatively correlated with RERG expression, and functions as an independent oncomiR for the higher incidence and poorer prognosis of breast cancer PMID: 27705918
Estradiol estrogen receptor-beta and PGE2 integrate at RERG, leading to increased endometriotic cell proliferation. PMID: 24992181
Results describe the mRNA expression of CRABP1, RERG, and GRP in pituitary adenomas. PMID: 21270509
Loss of RERG expression is associated with breast cancer and distant metastasis. PMID: 20697807
亞細胞定位:
Cytoplasm.
蛋白家族:
Small GTPase superfamily, Ras family
組織特異性:
Detected in heart, brain, placenta, lung, liver, skin, kidney and pancreas. Detected in estrogen receptor-positive breast-derived cell lines, but not in estrogen receptor-negative cell lines. Expression is decreased or lost in a significant proportion of