MXD4 Antibody
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中文名稱：MXD4兔多克隆抗體
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貨號(hào)：CSB-PA006661
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規(guī)格：￥1090
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：MXD4
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別名：bHLHc12 antibody; Class C basic helix loop helix protein 12 antibody; Class C basic helix-loop-helix protein 12 antibody; MAD 4 antibody; MAD4 antibody; Mad4 homolog antibody; MAD4_HUMAN antibody; Max associated protein 4 antibody; MAX dimerization protein 4 antibody; Max dimerizer 4 antibody; Max interacting transcriptional repressor MAD4 antibody; Max-associated protein 4 antibody; Max-interacting transcriptional repressor MAD4 antibody; MST 149 antibody; MST149 antibody; MSTP 149 antibody; MSTP149 antibody; MXD 4 antibody; MXD4 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse
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免疫原：Synthesized peptide derived from the N-terminal region of Human Mad 4.
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：IHC, ELISA
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推薦稀釋比：
Application Recommended Dilution IHC 1:100-1:300 ELISA 1:10000 -
Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
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基因功能參考文獻(xiàn)：
- The E3 ligase activity of c-IAP1 was not required for downregulation of Mad4 expression. PMID: 22895069
- regulation by a transcriptional repressor complex that contains Miz-1 and c-Myc PMID: 12418961
- Data suggest that the biological function of the interaction between T-complex protein 10-like and MAD4 may be to maintain the differentiation state in liver cells. PMID: 15469726
- replicative senescence-specific factors may block c-Myc inhibition of Miz-1 activation of hMad4 expression, and the continual presence of hMad4 protein may transcriptionally repress selected c-Myc target genes PMID: 16167342
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亞細(xì)胞定位：Nucleus.
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數(shù)據(jù)庫(kù)鏈接：
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