L1 Antibody

Name: L1 Antibody
Brand: CUSABIO
SKU: CSB-PA08359A0Rb

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說明書

產品詳情

產品描述：

The rabbit anti-human papillomavirus type 18 L1 polyclonal antibody was developed in the rabbit using the recombinant HPV18 major capsid protein L1 protein (1-568aa) as the immunogen. After immunization, the rabbit anti-serum was collected and then purified via protein G affinity chromatograph to obtain the high purity HPV18 L1 polyclonal antibody. Its purity is above 95%.

This HPV18 L1 polyclonal antibody can detect the HPV18 major capsid protein L1. And it has been quality validated for ELISA. It may help to study the roles of the HPV18 major capsid protein L1 in the HPV18 infection-associated research.
產品名稱：

Rabbit anti-Human papillomavirus type 18 L1 Polyclonal antibody
Uniprot No.：

P06794
基因名：

L1
別名：

L1 antibody; Major capsid protein L1 antibody
宿主：

Rabbit
反應種屬：

Human papillomavirus type 18
免疫原：

Recombinant HPV18 Major capsid protein L1 protein (1-568AA)
免疫原種屬：

Human papillomavirus type 18

標記方式：

Non-conjugated

本頁面中的產品，L1 Antibody (CSB-PA08359A0Rb)，的標記方式是Non-conjugated。對于L1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA08359B0Rb	L1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA08359C0Rb	L1 Antibody, FITC conjugated
Biotin	CSB-PA08359D0Rb	L1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.
基因功能參考文獻：
1. L1 sequences were strongly methylated in all cervical carcinomas studied; hypothesize that L1 is preferentially methylated after integration of the HPV genome into the cellular DNA PMID: 16472835
亞細胞定位：

Virion. Host nucleus.
蛋白家族：

Papillomaviridae L1 protein family
數據庫鏈接：

KEGG: vg:1489090

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