L1 Antibody, Biotin conjugated

^{Rare Species}

說明書

產品詳情

產品名稱：

Rabbit anti-Human papillomavirus type 18 L1 Polyclonal antibody
Uniprot No.：

P06794
基因名：

L1
別名：

L1 antibody; Major capsid protein L1 antibody
宿主：

Rabbit
反應種屬：

Human papillomavirus type 18
免疫原：

Recombinant HPV18 Major capsid protein L1 protein (1-568AA)
免疫原種屬：

Human papillomavirus type 18
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.
基因功能參考文獻：
1. L1 sequences were strongly methylated in all cervical carcinomas studied; hypothesize that L1 is preferentially methylated after integration of the HPV genome into the cellular DNA PMID: 16472835
亞細胞定位：

Virion. Host nucleus.
蛋白家族：

Papillomaviridae L1 protein family
數據庫鏈接：

KEGG: vg:1489090

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