KCNH7 Antibody, Biotin conjugated
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中文名稱：KCNH7兔多克隆抗體, Biotin偶聯
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貨號：CSB-PA878877LD01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) KCNH7 Polyclonal antibody
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Uniprot No.：
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基因名：KCNH7
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別名：KCNH7 antibody; ERG3Potassium voltage-gated channel subfamily H member 7 antibody; Ether-a-go-go-related gene potassium channel 3 antibody; ERG-3 antibody; Eag-related protein 3 antibody; Ether-a-go-go-related protein 3 antibody; hERG-3 antibody; Voltage-gated potassium channel subunit Kv11.3 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Potassium voltage-gated channel subfamily H member 7 protein (1-300AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly.
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基因功能參考文獻：
- we have discovered that, the Kv11.3 (hERG3) a plasma-membrane potassium channel plays a critical role in the regulation of autophagy in a melanoma cell model PMID: 26942884
- KCNH7 c.1181G>A had the highest enrichment among individuals with bipolar spectrum disorder (x2 5 7.3) and the strongest family-based association with bipolar 1 (P 5 0.021), bipolar spectrum (P 5 0.031) and any major affective disorder (P 5 0.016). PMID: 24986916
- The recombinant wild-type ERG3 protein produced in HEK cells generates two prominent bands. When the entire CNBD of ERG3 protein was deleted, only an EndoH-sensitive band was generated, indicating that this band constitutes the immature species. PMID: 15961404
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亞細胞定位：Membrane; Multi-pass membrane protein.
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蛋白家族：Potassium channel family, H (Eag) (TC 1.A.1.20) subfamily, Kv11.3/KCNH7 sub-subfamily
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組織特異性：Expressed in prolactin-secreting adenomas.
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數據庫鏈接：
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