GNPAT Antibody, HRP conjugated
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中文名稱：GNPAT兔多克隆抗體, HRP偶聯
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貨號：CSB-PA009629LB01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) GNPAT Polyclonal antibody
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Uniprot No.：
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基因名：GNPAT
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別名：Acyl CoA dihydroxyacetonephosphateacyltransferase antibody; Acyl-CoA:dihydroxyacetonephosphateacyltransferase antibody; DAP AT antibody; DAP-AT antibody; DAPAT antibody; DHAP AT antibody; DHAP-AT antibody; DHAPAT antibody; Dihydroxyacetone phosphate acyltransferase antibody; EC 2.3.1.42 antibody; Glycerone-phosphate O-acyltransferase antibody; Glyceronephosphate O acyltransferase antibody; GNPAT antibody; GNPAT_HUMAN antibody; OTTHUMP00000036147 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Dihydroxyacetone phosphate acyltransferase protein (589-680AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：HRP
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Dihydroxyacetonephosphate acyltransferase involved in plasmalogen biosynthesis.
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基因功能參考文獻：
- GNPAT p.D519G is strongly associated with markedly increased iron stores in p.C282Y homozygotes after correction for age, iron-related variables, and alcohol consumption. PMID: 27936396
- GNPAT rs11558492 is not a major modifier of iron status and is not associated with liver fibrosis in HFE-related Hemochromatosis patients. PMID: 28425416
- Here, we report the characterization of the recombinant human DHAP acyl-transferase, which performs the first step in alkyl-DHAP synthesis. PMID: 27836547
- Reduction of GNPAT activated NF-kappaB in glial cell lines and microglia in cortex. PMID: 28292831
- C282Y homozygotes referred for HFE testing commonly have a GNPAT variant. This GNPAT variant does not appear be a co-modifying gene affecting expression of HFE related hemochromatosis in this population. The GNPAT variant does not predict the severity of iron overload. PMID: 27740525
- The variant of the GNPAT gene showed the most significant association with severe iron overload. PMID: 25605615
- ACOX1 and GNPAT silencing up-regulated ceramide galactosyltransferase (UGT8) mRNA expression, and down-regulated UDP-glucoseceramide glucosyltransferase (UGCG). PMID: 23933200
- Novel mutations in GNPAT cause rhizomelic chondrodysplasia punctata (RCDP) type 2. PMID: 21990100
- peroxisomal DHAPAT is essential for the biosynthesis of plasmalogens in animal cells PMID: 15687349
- Chromosome 1q42.1 harbors GNPAT and DISC1 as candidate genes for schizophrenia. PMID: 16997000
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相關疾病：Rhizomelic chondrodysplasia punctata 2 (RCDP2)
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亞細胞定位：Peroxisome membrane; Peripheral membrane protein; Matrix side.
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蛋白家族：GPAT/DAPAT family
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數據庫鏈接：
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