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中文名稱：FTSJ1兔多克隆抗體
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貨號：CSB-PA009055LA01HU
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規格：￥440
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圖片：
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Western blot
All lanes: FTSJ1 antibody at 2µg/ml
Lane 1: HepG2 whole cell lysate
Lane 2: Mouse brain tissue
Lane 3: EC109 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/15000 dilution
Predicted band size: 37, 36 kDa
Observed band size: 37 kDa -
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA009055LA01HU at dilution of 1:50
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) FTSJ1 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：CDLIV antibody; FTSJ 1 antibody; FtsJ homolog 1 (E. coli) antibody; FtsJ homolog 1 antibody; FtsJ RNA methyltransferase homolog 1 antibody; FTSJ1 antibody; JM23 antibody; Mental retardation X linked 44 antibody; Mental retardation X linked 9 antibody; MRX44 antibody; MRX9 antibody; Protein ftsJ homolog 1 antibody; Putative ribosomal RNA methyltransferase 1 antibody; RRMJ1 antibody; RRMJ1_HUMAN antibody; rRNA (uridine 2' O ) methyltransferase antibody; rRNA (uridine-2''-O-)-methyltransferase antibody; SPB1 antibody; TRM7 antibody
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宿主：Rabbit
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反應種屬：Human, Mouse
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免疫原：Recombinant Human Putative tRNA (cytidine(32)/guanosine(34)-2\'-O)-methyltransferase protein (1-329AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
本頁面中的產品，FTSJ1 Antibody (CSB-PA009055LA01HU)，的標記方式是Non-conjugated。對于FTSJ1 Antibody，我們還提供其他標記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
引用文獻
- Investigating the Inhibition of FTSJ1 a Tryptophan tRNA-Specific 2′-O-Methyltransferase by NV TRIDs, as a Mechanism of Readthrough in Nonsense Mutated CFTR PS Carollo,biochemistry and molecular biology,2023
產品評價
相關產品
靶點詳情
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功能：Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.
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基因功能參考文獻：
- we have provided strong evidence that human FTSJ1 is required for Cm32 and Gm34 modification of tRNAPhe. PMID: 26310293
- May play a role in the regulation of translation. Mutations cause X-linked mental retardation. PMID: 15162322
- A splice site mutation is associated with non-syndromic mental retardation in a large Belgian family PMID: 15342698
- A 50kb deletion at Xp11.23 including the two genes, SLC38A5 and FTSJ1 was found in 3 brothers with moderate to severe mental retardation. PMID: 17333282
- identified a novel FTSJ1 mutation in an X-linked mental retardation family through mutation screening of a cohort of 73 unrelated Japanese male probands with MR PMID: 18081026
- Results suggest a positive association between genetic variants and nonsyndromic X-linked mental retardation in young male subjects in the Chinese Han population. PMID: 18401546
- These findings suggest that genetic variations in FtsJ homolog 1 (E. coli) possibly influence human cognitive ability. PMID: 19012053
- Spb1p is a homologous yeast nucleolar protein PMID: 10648622
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相關疾病：Mental retardation, X-linked 44 (MRX44)
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亞細胞定位：Cytoplasm.
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蛋白家族：Class I-like SAM-binding methyltransferase superfamily, RNA methyltransferase RlmE family, TRM7 subfamily
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組織特異性：Found in fetal brain, lung, liver and kidney. In the adult brain, expressed in amygdala, caudate nucleus, corpus callosum, hippocampus and thalamus.
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數據庫鏈接：
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