FBXL20 Antibody

中文名稱：

FBXL20兔多克隆抗體
貨號：

CSB-PA822228LA01HU
規格：

￥440
圖片：
IHC image of CSB-PA822228LA01HU diluted at 1:800 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) FBXL20 Polyclonal antibody
Uniprot No.：

Q96IG2
基因名：

FBXL20
別名：

FBXL20 antibody; FBL2F-box/LRR-repeat protein 20 antibody; F-box and leucine-rich repeat protein 20 antibody; F-box/LRR-repeat protein 2-like antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human F-box/LRR-repeat protein 20 protein (1-137AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，FBXL20 Antibody (CSB-PA822228LA01HU)，的標記方式是Non-conjugated。對于FBXL20 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA822228LB01HU	FBXL20 Antibody, HRP conjugated	ELISA
FITC	CSB-PA822228LC01HU	FBXL20 Antibody, FITC conjugated
Biotin	CSB-PA822228LD01HU	FBXL20 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:500-1:1000

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Role in neural transmission.
基因功能參考文獻：
1. which provides a signal to promote its ubiquitination and proteasomal degradation mediated by FBXL20 and the associated Skp1-Cullin1 complex, leading to inhibition of autophagy and receptor endocytosis PMID: 25593308
2. study concludes FBXL20 plays an essential role in the carcinogenesis of colorectal adenocarcinoma and promotes carcinogenesis through the regulation of the Wnt signaling pathway and caspase activation PMID: 23023584
亞細胞定位：

Cytoplasm.
數據庫鏈接：

HGNC: 24679

OMIM: 609086

KEGG: hsa:84961

STRING: 9606.ENSP00000264658

UniGene: Hs.462946

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