DIRAS1 Antibody
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中文名稱：DIRAS1兔多克隆抗體
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貨號(hào)：CSB-PA006905GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：DIRAS1
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別名：DIRAS1 antibody; GBTS1 antibody; RIGGTP-binding protein Di-Ras1 antibody; Distinct subgroup of the Ras family member 1 antibody; Ras-related inhibitor of cell growth antibody; Rig antibody; Small GTP-binding tumor suppressor 1 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human DIRAS1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
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靶點(diǎn)詳情
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功能：Displays low GTPase activity and exists predominantly in the GTP-bound form.
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基因功能參考文獻(xiàn)：
- This neuronal DIRAS1 gene with a proposed role in cholinergic transmission provides not only a candidate for human myoclonic epilepsy but also insights into the disease etiology, while establishing a spontaneous model for future intervention studies and functional characterization. PMID: 28223533
- Results show that DIRAS1 is frequently methylated in human colorectal cancer and the expression of DIRAS1 is silenced by promoter region methylation. PMID: 28491151
- DiRas1 expression inhibits malignant features of cancers in part by nonproductively binding to SmgGDS and inhibiting the binding of other small GTPases to SmgGDS PMID: 26814130
- DIRAS1 downregulation is associated with esophageal squamous cell carcinoma metastasis. PMID: 23436800
- a novel Ras-related protein and potential neural tumor suppressor (RIG) PMID: 12107278
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亞細(xì)胞定位：Cell membrane; Lipid-anchor; Cytoplasmic side.
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蛋白家族：Small GTPase superfamily, Di-Ras family
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組織特異性：Highly expressed in heart and brain.
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數(shù)據(jù)庫(kù)鏈接：
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