CRISPLD2 Antibody

中文名稱：

CRISPLD2兔多克隆抗體
貨號：

CSB-PA884430LA01HU
規(guī)格：

￥440
圖片：
Western blot
All lanes: CRISPLD2 antibody at 2μg/ml
Lane 1: Jurkat whole cell lysate
Lane 2: CEM whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 56, 52, 43, 18, 14 kDa
Observed band size: 56 kDa
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) CRISPLD2 Polyclonal antibody
Uniprot No.：

Q9H0B8
基因名：

CRISPLD2
別名：

CRISP-11 antibody; CRISP11 antibody; Crispld2 antibody; CRLD2_HUMAN antibody; Cysteine-rich secretory protein 11 antibody; Cysteine-rich secretory protein LCCL domain-containing 2 antibody; DKFZP434B044 antibody; LCCL domain-containing cysteine-rich secretory protein 2 antibody; LCRISP2 antibody; MGC74865 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Cysteine-rich secretory protein LCCL domain-containing 2 protein (40-305AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁面中的產(chǎn)品，CRISPLD2 Antibody (CSB-PA884430LA01HU)，的標(biāo)記方式是Non-conjugated。對于CRISPLD2 Antibody，我們還提供其他標(biāo)記。見下表：

標(biāo)記方式	貨號	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA884430LB01HU	CRISPLD2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA884430LC01HU	CRISPLD2 Antibody, FITC conjugated
Biotin	CSB-PA884430LD01HU	CRISPLD2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:1000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

功能：

Promotes matrix assembly.
基因功能參考文獻：
1. Our results suggest that CRISPLD2 rs4783099 may represent a risk factor for NSCPO (non-syndromic oral clefts). PMID: 27328068
2. Data suggest that suppression of CRISPLD2 increases the risk of lung inflammation in early life and adulthood. PMID: 27597766
3. Our data suggest that CRISPLD2 may have a unique anti-HMGB1 effect via miRNA155 and play an important role in immune balance. PMID: 26624800
4. CRISPLD2 is a target of progesterone receptor and its expression is decreased in women with endometriosis. PMID: 24955763
5. Results demonstrate genetic polymorphism of CRISPLD2 gene is associated with an increased risk of non-syndromic cleft lip with or without cleft palate. PMID: 25496823
6. findings define a role for LGL1 in fibroblast expansion and migration, epithelial cell migration, and mesenchymal-epithelial signaling, key processes in fetal lung development. PMID: 25480331
7. results support the hypothesis that variants in the CRISPLD2 gene may be involved in the etiology of NS CL(P). PMID: 20815724
8. Both LCCL-domains of human CRISPLD2 have high affinity for lipid A. PMID: 24090571
9. There is a decreased expression of CRISPLD2 in septic shock and it is association with procalcitonin in sepsis. PMID: 23799041
10. CRISPLD2 gene contributes to the etiology of NSCLP in the Northwestern Chinese population. SNP rs1546124 is significantly related to NSCLP, associated with both CL/P and CPO groups, and SNP rs4783099 is significantly associated with CPO. PMID: 21800413
11. the present investigation did not support the hypothesis of the involvement of CRISPLD2 in nonsyndromic cleft lip and palate PMID: 21244519
12. three SNPs in northern Chinese population found an association between these polymorphisms and NSCLP in both single-marker and haplotype analyses. data further strengthen the conclusion that altered CRISPLD2 is associated with NSCLP susceptibility. PMID: 20662919
13. CRISPLD2 is expressed in the mandible, palate and nasopharynx regions during craniofacial development at E13.5-E17.5, respectively. Altogether, these data suggest that genetic variation in CRISPLD2 has a role in the etiology of NSCLP. PMID: 17616516
14. present work introduces mammal CRISPLD2 as a major serum protein that acts as a natural LPS antagonist and promises to be of considerable preventative value against endotoxic shock. PMID: 19864597
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亞細胞定位：

Secreted.
蛋白家族：

CRISP family
數(shù)據(jù)庫鏈接：

HGNC: 25248

OMIM: 612434

KEGG: hsa:83716

STRING: 9606.ENSP00000262424

UniGene: Hs.513779

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