CA6 Antibody

說明書

中文名稱：

CA6兔多克隆抗體
貨號：

CSB-PA167607
規(guī)格：

￥2024
圖片：
Western blot analysis of extracts from LOVO cells and HepG2 cells, using CA6 antibody.
其他：

產(chǎn)品詳情
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) CA6 Polyclonal antibody
Uniprot No.：

P23280
基因名：

CA6
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Synthesized peptide derived from internal of Human CA6.
免疫原種屬：

Homo sapiens (Human)
克隆類型：

Polyclonal
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:3000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

功能：

Reversible hydration of carbon dioxide. Its role in saliva is unknown.
基因功能參考文獻(xiàn)：
1. The current study suggests that genetic variation in TAS2R38 and CA6 influences picky eating in preschoolers. PMID: 28858874
2. Anti-CA6 was the most prevalent novel autoantibody in patients with dry eye, and was associated with younger age and more severe disease. Longitudinal studies are needed to determine whether anti-CA6 is a marker for early Sjogren's syndrome. PMID: 29504954
3. CA6 is a specific marker for serous acinar cells of salivary glands and acinic cell carcinoma (AciCC). PMID: 26212680
4. genetic association studies in population of elderly women in Poland: Data suggest that SNPs in TAS2R38 (rs713598, rs1726866, rs10246939) and an SNP in CA6 (rs2274333) are associated with intake of and preferences for some foods (coffee and white cabbage) among the population studied. (TAS2R38 = taste receptor type 2 member 38; CA6 = carbonic anhydrase VI) PMID: 28455260
5. Results found that the CA VI gene polymorphism rs2274327 showed no correlation between salivary parameters and dental-oral health status in Eastern Anatolian Turkish children. PMID: 27100223
6. dental plaque amount, lactobacilli count, age, and saliva buffer capacity, as well as CA6 (T55M) gene polymorphism, explained total of 87.8% of variations in DMFT scores. PMID: 26377569
7. We also found that the haplotype (ACA) (rs2274328, rs17032907 and rs11576766)of the carbonic anhydrase VI was associated with a low number of decayed, missing, and filled teeth index with an odds ratio (95% confidence interval) of 0.635 (0.440-0.918). PMID: 26125798
8. Study showed that PROP (6-n-propylthiouracil) bitterness was due to TAS2R38 diplotypes, whereas the density of fungiform papillae was more closely associated with gustin genotypes PMID: 25447475
9. SNPs associated with taste perception and taste bud anatomy PMID: 24534176
10. results suggest that polymorphisms in the CA6 gene are associated with the concentrations of secreted CA VI. PMID: 23652931
11. The rs2274333 polymorphism of the gustin gene affects PROP sensitivity. PMID: 24040192
12. The aim of this study was to investigate carbonic anhydrase (CA) VI Exon 2 single nucleotide polymorphism (SNP) and its possible association with salivary parameters in type 2 diabetic patients compared to healthy adults. PMID: 22198626
13. The 1.9A crystal structure of the human CA VI catalytic domain reveals a prototypical mammalian CA fold, and a novel dimeric arrangement as compared to previously-reported CA structures. PMID: 22366092
14. The data of this study showed how the combination of the TAS2R38 and gustin gene genotypes modulate PROP phenotype. PMID: 21712049
15. The polymerase chain reaction followed by restriction fragment length polymorphism assay described here can be used as an alternative to sequencing in bitter taster status research, and could be employed as a survey tool in nutrigenomic studies. PMID: 21631296
16. The gustin gene dimorphism rs2274333 observed in supertaster and nontaster subjects may influence the protein conformation and, thereby, affect zinc ion binding. PMID: 20631203
17. analysis of allele & genotype distribution of 3 polymorphisms in CA6 gene; no association between polymorphisms in exons 2 & 3 & caries experience; positive association between salivary buffer capacity & rs2274327 PMID: 19721466
18. The cloning, expression and purification of this isozyme are reported. PMID: 17499996
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亞細(xì)胞定位：

Secreted.
蛋白家族：

Alpha-carbonic anhydrase family
組織特異性：

Major constituent of saliva.
數(shù)據(jù)庫鏈接：

HGNC: 1380

OMIM: 114780

KEGG: hsa:765

STRING: 9606.ENSP00000366662

UniGene: Hs.100322

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