CA5B Antibody

說(shuō)明書(shū)

產(chǎn)品詳情

Uniprot No.：

Q9Y2D0
基因名：

CA5B
別名：

CA VB antibody; CA-VB antibody; CA5B antibody; CAH5B_HUMAN antibody; Carbonate dehydratase VB antibody; Carbonic anhydrase 5B antibody; Carbonic anhydrase 5B; mitochondrial antibody; Carbonic anhydrase VB antibody; Carbonic anhydrase VB; mitochondrial antibody; mitochondrial antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human CA5B
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Reversible hydration of carbon dioxide.
基因功能參考文獻(xiàn)：
1. In 10 of 96 patients, mutations in CA5A were identified on both alleles but none in CA5B. Exhibiting decreased enzyme activity or thermal stability, all CAVA mutations were proven to cause disease, whereas the three variants showed no relevant effect PMID: 26913920
2. activators enhanced kcat, with no effect on KM, favoring the RDS in the catalytic cycle; the activation pattern of the two mitochondrial isoforms is very different from each other and as compared to those of the cytosolic isoforms hCA I and II. PMID: 17174092
亞細(xì)胞定位：

Mitochondrion.
蛋白家族：

Alpha-carbonic anhydrase family
組織特異性：

Strongest expression in heart, pancreas, kidney, placenta, lung, and skeletal muscle. Not expressed in liver.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 1378

OMIM: 300230

KEGG: hsa:11238

STRING: 9606.ENSP00000314099

UniGene: Hs.653287

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