ARNT2 Antibody
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中文名稱：ARNT2兔多克隆抗體
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貨號：CSB-PA864024ESR1HU
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規格：￥440
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圖片：
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Western blot
All lanes: Aryl hydrocarbon receptor nuclear translocator 2 antibody at 4μg/ml + Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 79, 78 kDa
Observed band size: 79 kDa -
Immunohistochemistry of paraffin-embedded human glioma using CSB-PA864024ESR1HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) ARNT2 Polyclonal antibody
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Uniprot No.：
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基因名：ARNT2
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別名：ARNT protein 2 antibody; ARNT2 antibody; ARNT2_HUMAN antibody; Aryl hydrocarbon receptor nuclear translocator 2 antibody; bHLHe1 antibody; Class E basic helix-loop-helix protein 1 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Aryl hydrocarbon receptor nuclear translocator 2 protein (440-690AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:200-1:1000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Transcription factor that plays a role in the development of the hypothalamo-pituitary axis, postnatal brain growth, and visual and renal function. Specifically recognizes the xenobiotic response element (XRE).
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基因功能參考文獻：
- The single nucleotide polymorphisms rs4778599 in the gene encoding aryl hydrocarbon receptor nuclear translocator 2 (ARNT2), showed an association that survived correction for multiple testing with emotion recognition of audio-visual stimuli in women PMID: 29194499
- Attenuated ARNT2 expression in HCC827 cells greatly promoted tumor growth. PMID: 25613063
- nominal associations were found between autism spectrum disorder scores and single-nucleotide polymorphisms in OXT, ARNT2 and CD38 PMID: 24635660
- Data suggest that selected human SIM1 (single-minded homolog 1) variants exhibit poor dimerization with ARNT2 and anomalous intracellular localization; these data were used to predict 'hot-spot' in SIM1/SIM2 (residues 290-326) critical for function. PMID: 24814368
- These results provide insight into the mechanisms of NPAS4/ARNT dimerisation and transcriptional activation. PMID: 24465693
- mutation of ARNT2 results in absence of detectable levels of ARNT2 transcript and protein from patient fibroblasts compared with controls, consistent with nonsense-mediated decay of the mutant transcript and loss of ARNT2 function. PMID: 24022475
- In white males, rs4072568 in ARNT2 was also associated with BMI (P = 9 x 10(-4)) and % body fat (P = 0.001). PMID: 21512513
- ARNT2 might play an important role in the modulation of HIF-1-regulated signaling and metabolism. PMID: 21945317
- promotes differentiation of IL-22-producing CD4(+) T-cells PMID: 20706985
- There is no association of ARNT2 gene with cleft palate only (n = 45) and cleft lip/palate (n = 37). PMID: 12210012
- We thus propose that NDN regulates neuronal function and hypoxic response by regulating the activities of the ARNT2:SIM1 and ARNT2:HIF1alpha dimers, respectively. PMID: 17826745
- a possible use of ARNT2 and GST A1 as prognostic breast cancer biomarkers. PMID: 17899366
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相關疾病：Webb-Dattani syndrome (WEDAS)
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亞細胞定位：Nucleus.
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數據庫鏈接：
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