ARHGEF10 Antibody
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中文名稱：ARHGEF10兔多克隆抗體
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貨號：CSB-PA176345
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA176345(ARHGEF10 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA176345(ARHGEF10 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)
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其他：
產品詳情
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Uniprot No.：
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基因名：ARHGEF10
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別名：ARHGA_HUMAN antibody; ARHGEF10 antibody; DKFZp686H0726 antibody; GEF10 antibody; KIAA0294 antibody; MGC131664 antibody; Rho guanine nucleotide exchange factor (GEF) 10 antibody; Rho guanine nucleotide exchange factor 10 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Fusion protein of Human ARHGEF10
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 IHC 1:50-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：May play a role in developmental myelination of peripheral nerves.
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基因功能參考文獻：
- Ectopic expression of an N-terminal-truncated ARHGEF10 mutant led to the generation of large vesicle-like structures containing both Rab6 and Rab8. PMID: 27550519
- This study provided new insights into the roles of ARHGEF10 SNPs rs2280887, rs9657362, and rs4480162 in the development and progression of ischemic stroke in northern Chinese Han population. PMID: 27934548
- A significant association of ARHGEF10 with paclitaxel chemotherapy induced peripheral neuropathy was found. PMID: 26143528
- Identification of a negative regulatory region for the exchange activity and characterization of T332I mutant of Rho guanine nucleotide exchange factor 10 (ARHGEF10). PMID: 21719701
- the rs4376531 polymorphism in the ARHGEF10 gene is a risk factor for atherothrombotic stroke in the Han Chinese population PMID: 21743172
- The functional single-nucleotide polymorphism of ARHGEF10 confers the susceptibility to atherothrombotic stroke. PMID: 20042462
- data support a role for ARHGEF10 in developmental myelination of peripheral nerves PMID: 14508709
- Gef10 is the third member of a Rho-specific GEF family with unusual protein architecture PMID: 16896804
- A novel RhoA-dependent signaling pathway under the control of ARHGEF10 has a pivotal role in the regulation of the cell division cycle. PMID: 19635168
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相關疾病：Slowed nerve conduction velocity (SNCV)
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