AMPH Antibody
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中文名稱：AMPH兔多克隆抗體
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貨號：CSB-PA001683GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：Amp antibody; AMPH 1 antibody; AMPH antibody; AMPH_HUMAN antibody; AMPH1 antibody; Amphiphysin (Stiff-Man syndrome with breast cancer 128kD autoantigen) antibody; Amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen) antibody; Amphiphysin antibody; Amphiphysin I antibody; CG8604 antibody; Damp antibody; dAmph antibody; Dmel\CG8604 antibody; HGNC:471 antibody; MGC49429 antibody; Stiff man syndrome with breast cancer 128kD autoantigen antibody; Stiff man syndrome with breast cancer 128kDa autoantigen antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human AMPH
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.
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基因功能參考文獻：
- The data show that the dynamin-amphiphysin helices are rearranged to form clusters upon GTP hydrolysis and membrane constriction occurs at protein-uncoated regions flanking the clusters. PMID: 29357276
- We show that AMPH-1/BIN1 binds to nesprin and actin, as well as to the microtubule-binding protein CLIP170 in both species. We propose that BIN1 has a direct and evolutionarily conserved role in nuclear positioning, altered in myopathies. PMID: 26506308
- It is a nerve protein and its autoantibody causes paraneoplastic neurological syndromes. PMID: 25087559
- AMPH1 protein level is reduced in transgenic mouse brain proteins. in the brainstem of nontransgenic and terminally ill JNPL3 transgenic mice. PMID: 22975846
- We propose that antibody-mediated amphiphysin deficiency may account for anxiety behavior in stiff person syndrome PMID: 22331304
- structure-based approach to prediction of peptide-binding behavior of SH3 domain of amphiphysin-1: statistical modeling PMID: 19669081
- investigation of binding affinities of decapeptide ligands with amphiphysin SH3 domain using QSAR models PMID: 20214647
- Female patient with amphiphysin autoantibodies and siff leg syndrome due to small cell cancer of the lung. PMID: 16671079
- Amphiphysin I (Amph I) is a minibrain kinase/dual-specificity tyrosine phosphorylation-regulated kinase substrate. Amph I phosphorylation changes the recruitment of endophilin at the endocytic sites. PMID: 16733250
- This study demonstrates that the analysis of the molecular interaction energy components between peptides and the SH3 domain can successfully characterize the binding interface. PMID: 18206907
- Analyses of Gaussian distribution models showed that diversified properties contribute to the interactions between the SH3 domain and of amphiphysin and peptides. PMID: 18814309
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亞細胞定位：Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton.
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組織特異性：Neurons, certain endocrine cell types and spermatocytes.
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數據庫鏈接：
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