Rat Corticosterone,CORT ELISA Kit

Rat Corticosterone,CORT ELISA Kit

產品詳情

引用文獻

產品評價

靶點詳情

產品詳情

引用文獻

產品評價

相關產品

靶點詳情

Most popular with customers

產品中心

信號通路

技術信息

聯系信息

文獻引用 (47) 說明書下載

中文名稱：

大鼠皮質酮(CORT)酶聯免疫試劑盒
貨號：

CSB-E07014r
規格：

96T/48T
價格：

￥3900/￥2500
其他：

產品詳情
產品評價
引用文獻
相關產品
靶點詳情

產品描述：

大鼠皮質酮/腎上腺酮(CORT)酶聯免疫試劑盒（CSB-E07014r）為競爭法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的CORT含量。CORT即皮質酮，是一種重要的糖皮質激素。它參與機體應激反應與代謝調節等生理過程。研究機制上，主要通過與細胞內糖皮質激素受體結合，調控相關基因表達，影響細胞功能，在神經、內分泌等多系統中發揮關鍵作用。試劑盒檢測范圍為0.2 ng/mL-40 ng/mL，支持科研人員開展神經內分泌機制研究、慢性應激模型評估、代謝綜合征相關實驗及藥物干預效果驗證等領域的探索，為行為學實驗、神經藥理學研究和激素調控機制探索提供可靠的數據支持。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
別名：

N/A
縮寫：

CORT
種屬：

Rattus norvegicus (Rat)
樣本類型：

serum, plasma, tissue homogenates
檢測范圍：

0.2 ng/mL-40 ng/mL
靈敏度：

0.1 ng/mL
反應時間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領域：

Signal Transduction
測定原理：

quantitative
測定方法：

Competitive

精密度：

線性度：

To assess the linearity of the assay, samples were spiked with high concentrations of rat CORT in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
	Sample	Serum(n=4)
1:1	Average %	84
	Range %	80-91
1:2	Average %	90
	Range %	85-95
1:4	Average %	97
	Range %	92-103
1:8	Average %	105
	Range %	100-112

回收率：

The recovery of rat CORT spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.

Sample Type	Average % Recovery	Range
Serum (n=5)	95	89-99
EDTA plasma (n=4)	92	88-97

標準曲線：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

ng/ml	OD1	OD2	Average
40	0.138	0.132	0.135
10	0.239	0.258	0.249
3.2	0.504	0.509	0.507
0.8	0.939	1.009	0.974
0.2	1.419	1.424	1.422
0	2.154	2.159	2.157

數據處理：

ELISA操作視頻及標曲繪制軟件下載
貨期：

3-5 working days

Effects of restraint stress and orthodontic treatment on physical and psychological states in rats Y Cheng, H Nie, J Qian, J Lu, Y Li, H Li,Journal of the World Federation of Orthodontists,2024
Aging induced Hematological, Anthropometrical, Biochemical, and Reproductive Changes in Male Rats KH Mohamed,Zagazig Veterinary Journal,2024
The effect of late-life environmental enrichment on stress and anxiety: the role of sex and age-related differences in coping with aversive stimuli M Balietti,Heliyon,2024
Environmental enrichment and the combined interventions of EE and metformin enhance hippocampal neuron survival and hippocampal-dependent memory in type 2 diabetic rats under stress through the BDNF-TrkB signaling pathways TR Ismail,Biomedicine & pharmacotherapy,2024
Ketamine causes poor maternal care in rats with postpartum depression and leads to few behavioral and neurochemical alterations on male offspring J Zaccarelli-Magalh?es,Behavioural brain research,2023
Increase of circulating cfDNA by chronic training or overtraining in human and rat and its possible mechanisms LJ Yin,Science & Sports,2023
Association analysis of gut microbiota-metabolites-neuroendocrine changes in male rats acute exposure to simulated altitude of 5500 m J Wang,Scientific reports,2023
Can Resveratrol Influence the Activity of 11β-Hydroxysteroid Dehydrogenase Type 1? A Combined In Silico and In Vivo Study J Novak,Pharmaceuticals,2023
Paradoxical Anxiety Level Reduction in Animal Chronic Stress: A Unique Role of Hippocampus Neurobiology Vadim Tseilikman,International Journal of Molecular Sciences,2022
Circ_0000181 regulates miR-667-5p/NLRC4 axis to promote pyroptosis progression in diabetic nephropathy Y Li,Scientific reports,2022
The extent of involvement of ouabain, hippocampal expression of Na+/K+-ATPase, and corticosterone/melatonin receptors ratio in modifying stress-induced behavior differs according to the stressor in context S Abdelmissih,Brazilian journal of medical and biological research,2022
Total Saikosaponins Attenuates Depression-Like Behaviors Induced by Chronic Unpredictable Mild Stress in Rats by Regulating the PI3K/AKT/NF-κB?… Z Zhou,Evidence-Based Complementary and Alternative Medicine,2022
The Link between Activities of Hepatic 11beta-Hydroxysteroid Dehydrogenase-1 and Monoamine Oxidase-A in the Brain Following Repeated Predator Stress: Focus on Heightened Anxiety V Tseilikman,International journal of molecular sciences,2022
Jie-Yu-He-Huan Capsule Ameliorates Anxiety-Like Behaviours in Rats Exposed to Chronic Restraint Stress via the cAMP/PKA/CREB/BDNF Signalling Pathway Xiwen Geng,Oxidative Medicine and Cellular Longevity,2021
Neurotoxic Effect of Fipronil in Male Wistar Rats: Ameliorative Effect of L-Arginine and L-Carnitine YK Mahmoud,Biology,2021
PET neuroimaging reveals upregulation of dopamine D2 receptor contributes to amygdaloid dysfunction in rat acute restraint stress model Z Yan,Biochemical and Biophysical Research Communications,2021
Norepinephrine in the dentate gyrus is involved in spatial learning and memory alteration induced by chronic restraint stress in aged rats FX Wang,Neuroreport,2020
Effect of Light-Dark Cycle Misalignment on the Hypothalamic-Pituitary-Gonadal Axis, Testicular Oxidative Stress, and Expression of Clock Genes in Adult Male Rats A Moustafa,International journal of endocrinology,2020
Changes in nitric oxide, carbon monoxide, hydrogen sulfide and male reproductive hormones in response to chronic restraint stress in rats A Moustafa,Free Radical Biology and Medicine,2020
Swim therapy-induced tissue specific metabolic responses in male rats A Moustafa,Life Sciences,2020
MODULATION OF DEPRESSION-LIKE BEHAVIOR BY A COMBINATION WITH VITAMIN D3 AND 17Β-ESTRADIOL IN MIDDLE-AGED OVARIECTOMIZED RATS SUBJECTED TO CHRONIC MILD STRESS V Mironova,Opera Medica et Physiologica,2020
The Involvement of Notch1 Signaling Pathway in Mid-aged Female Rats under Chronic Restraint Stress J Shen,Neuroscience Letters,2020
Saponin extract of Baihe-Zhimu Tang ameliorates depression in chronic mild stress rats D Jia,Journal of Functional Foods,2020
Hyperfunction of the stress response system and novelty┸\induced hyperactivity correlate with enhanced cocaine┸\induced conditioned place preference in NCAM … B K盲hler,Addict Biol,2020
Increased Oxidative Damage Contributes to Mitochondrial Dysfunction in Muscle of Depressed Rats Induced by Chronic Mild Stress Probably Mediated by SIRT3 … Q Xiao,ANIMAL AND HUMAN PHYSIOLOGY,2020
Vitamin D3 attenuates anxiety-like behavior in long-term ovariectomized rats with unpredictable mild stress BARANENKO D,BIOCELL,2019
Synergic action of Vitamin D3 and 17β-estradiol on behavioral impairments induced by unpredictable mild stress in the adult ovariectomized female rats Fedotova J, et al,Biorxiv,2019
Mechanisms of Stress-Induced Spermatogenesis Impairment in Male Rats Following Unpredictable Chronic Mild Stress (uCMS) Zou P, et al,International Journal of Molecular Sciences,2019
Metabolomic signatures and microbial community profiling of depressive rat model induced by adrenocorticotrophic hormone Song J, et al,Journal of Translational Medicine,2019
Acute restraint stress alters food-foraging behavior in rats: Taking the easier Way while suffered Tu BX,Brain Research Bulletin,2019
Chronic paradoxical sleep deprivation-induced depression Ma W, et al,Life Sciences,2019
Changes in Secretory Activity of Adrenal Zona Fasciculata Cells in Pubertal Rats Exposed to Low Doses of DDT in Different Periods of Ontogeny Yaglova NV, et al,Bulletin of experimental biology and medicine,2018
Social defeat stress before pregnancy induces depressive-like behaviours and cognitive deficits in adult male offspring: correlation with neurobiological changes Wei S.et al,BMC Neuroscience,2018
Transplantation of bone marrow mesenchymal stem cells reduces GluR1 expression in the hippocampus and amygdala and affects secretion of stress-related hormones in rats with spinal cord injuries: a potential anti-chronic stress mechanism Jia-Jia Sun.et al,INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE,2018
Perfluorooctane sulfonate (PFOS) can alter the hypothalamic?pituitary?adrenal (HPA) axis activity by modifying CRF1 and glucocorticoid receptors R. Salgado.et al,Toxicology Letters,2018
Antidepressant-like effect of lipid extract of Channa striatus in postpartum model of depression in rats Abdul Shukkoor MS.et al,Evid Based Complement Alternat Med,2016
Acupuncture alters pro-inflammatory cytokines in the plasma of maternally separated rat pups Wang Z.et al,Chin J Integr Med. ,2017
Role of early environmental enrichment on the social dominance tube test at adulthood in the rat Cao WY.et al,Psychopharmacology (Berl).,2017
Protective effects of carnosol against oxidative stress induced brain damage by chronic stress in rats Samarghandian S.et al,BMC Complement Altern Med.,2017
Curcumin reverses the depressive-like behavior and insulin resistance induced by chronic mild stress Shen JD.et al,Metab Brain Dis.,2017
Exogenous hydrogen sulfide eliminates spatial memory retrieval impairment and hippocampal CA1 LTD enhancement caused by acute stress via promoting glutamate uptake He J.et al,Neuroscience,2017
THERAPEUTICS FOR THE INDUCTION OF ENDOGENOUS STEROIDOGENESIS AND METHODS ASSOCIATED WITH THEIR IDENTIFICATION Papadopoulos V.et al, U.S. Patent ,2016
Insulin-like growth factor 2 mitigates depressive behavior in a rat model of chronic stress. Luo YW.et al,Neuropharmacology.,2015
Protective Effects of Carvacrol against Oxidative Stress Induced by Chronic Stress in Rat's Brain, Liver, and Kidney Saeed Samarghandian. et al,Biochemistry Research International,2016
Effect of chrysin on nociception in formalin test and serum levels of noradrenalin and corticosterone in rats Gheibi N et al,Basic Clin Neurosci,2015
Regulation of corticosterone secretion is modified by PFOS exposure at different levels of the hypothalamic-pituitary-adrenal axis in adult male rats Pereiro N et al,Toxicol Lett,2014
Orcinol glucoside produces antidepressant effects by blocking the behavioural and neuronal deficits caused by chronic stress Ge JF et al,Eur Neuropsychopharmacol,2013

收起更多

最新研究進展：

CORT是一種重要的激素，可以影響多種生理過程，如免疫和應激反應。最近的研究表明，CORT可以通過影響免疫細胞的活動來調節免疫反應。例如，在炎癥過程中，CORT可以抑制炎癥介質的產生，從而緩解炎癥反應。此外，CORT也被認為是抑制免疫系統過度激活的重要因素之一。最近的研究還表明，CORT可能在多種神經系統疾病中具有治療潛力，例如抑郁癥和焦慮癥等。

Intra-assay Precision (Precision within an assay): CV%<15%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<15%

Three samples of known concentration were tested in twenty assays to assess.