1. coordinated upregulation of genes encoding CRP, interleukin-6 (IL-6), HNF1alpha, and HNF4alpha in the livers and white adipose tissue (WAT) of chronic renal failure rats, as compared to the pair-fed and control animals. PMID: 29330688
2. CRP: varied between DJOS and SHAM groups maintained on HF/HF, CD/CD, and CD/HF. PMID: 29849871
3. Fibrinopeptide A induces CRP expression in Vascular Smooth Muscle Cells via Reactive Oxygen Species-ERK1/2/p38-NF-kappaB signal pathway. PMID: 29768263
4. Knockdown of ZFAS1 or miR-150 overexpression effectively relieved AMI-induced myocardial infarction in AMI-1 week rats. The ZFAS1/miR-150 axis was involved in the molecular mechanism of AMI induced cardiomyocytes apoptosis via regulating CRP PMID: 28295592
5. Epigallocatechin-3-gallate inhibits Ang II-induced CRP generation by interfering with AT1-ROS-ERK1/2 signal pathway in hepatocytes, preventing inflammation. PMID: 27492718
6. Salvianolic acid B exerted anti-steatotic and anti-inflammatory effects against alcoholic liver injury by inducing SIRT1-mediated inhibition of CRP and ChREBP expression. PMID: 27989594
7. Rosiglitazone inhibits angiotensin II-induced C-reactive protein generation by interfering with AT1-ROS-ERK1/2/JNK signal pathway and up-regulating PPARgamma expression in hepatocytes PMID: 26741265
8. These findings provide evidence that, in the presence of high CRP levels, rosuvastatin exhibits significant anti-inflammatory, anti-oxidative, and renoprotective effects. PMID: 25536316
9. Data show that palmitic acid significantly stimulated mRNA and protein expression of C-reactive protein, inducible nitric oxide synthase and tumor necrosis factor-alpha in vascular smooth muscle cells in time- and concentration-dependent manners. PMID: 25242580
10. No correlation was found between CRP levels and microvascular or macrovascular dysfunction in adjuvant-induced arthritis. PMID: 25708190
11. Homocysteine initiates an inflammatory response in VSMCs by stimulating CRP production via the NMDAr-ROS-ERK1/2/p38-NF-kappaB signal pathway. PMID: 25016361
12. CRP and IgM depositions demonstrate a parallel time course throughout the reperfusion to hepatocellular damage, inflammatory response and activated complement deposition in an ischemia-reperfusion model. PMID: 24642533
13. These demonstrate that aldosterone is able to induce CRP expression via MR-ROS-ERK1/2-NF-kappaB signal pathway in VSMCs, which provides a new evidence for the proinflammatory and proatherosclerotic effects of aldosterone. PMID: 25109280
14. Monomeric CRP localized with inflammatory cells in infarcted myocardium. Intravenous pCRP administration significantly enhanced leukocyte rolling, adhesion, and transmigration via localized dissociation to mCRP in inflamed cremaster muscle. PMID: 24982116
15. In older animals, there is depressed PAP expression related to a blunted inflammatory response in acute pancreatitis which is associated with worsened bacterial infiltration and higher C-reactive protein level PMID: 22807607
16. PDIA3 might be potentially involve into the occurence and development of acute rejection response in renal transplantation and increased plasma IL-2, IL-4, IL-6, and CRP levels play an important role to prevent acute kidney allograft rejection in rats. PMID: 22201020
17. C-reactive protein down-regulates endothelial nitric oxide synthase expression and promotes apoptosis in endothelial progenitor cells through receptor for advanced glycation end-products PMID: 22301267
18. After attachment of polymeric CRP to the surface of necrotic cardiomyocytes, generation of monomeric CRP was demonstrated over a period of 18 h. PMID: 21856781
19. This finding could indicate a possible role for CRP in the progression of small vessel disease in the brain and provide a therapeutic target PMID: 21840509
20. C-reactive protein and tumour necrosis factor-alpha are elevated in collagen-induced arthritis in Dark Agouti rats PMID: 21633874
21. Increased levels of CRP are an early sign of alcoholic fatty liver in rats. PMID: 21806828
22. C-reactive protein exerts a proinflammatory action via Toll-like receptor 4-dependent signaling pathway (AT(1)R-p38 MAPK-TLR4-PKCalpha) in rat vascular smooth muscle cells. PMID: 20332628
23. CRP may cause insulin resistance by increasing IRS-1 phosphorylation at Ser(307) and Ser(612) via JNK and ERK1/2, respectively, leading to impaired insulin-stimulated glucose uptake, GLUT4 translocation, and glycogen synthesis PMID: 17279354
24. the Ala12 allele of PPARG2 may be an independent factor associated with low serum hs-CRP levels in Japanese females PMID: 17574226
25. levels of C-reactive protein and adiponectin are improved after exercise training in diabetic rats PMID: 17660720
26. CRP and IgM depositions correlated well with local complement activation, which suggests a role of these molecules in complement activation PMID: 17981193
27. CRP levels and cardiovascular disease risk and the long term clinical outcome after acute coronary syndrome but such correlation has yet to be proven regarding CRP and atherosclerosis. PMID: 18254451
28. C-reactive protein stimulates superoxide anion release and tissue factor activity in vivo PMID: 18621373
29. CRP at clinically relevant concentrations (10 to 20 microg/mL) causes a disruption of the blood-brain barrier PMID: 19246692
30. The results suggest that CRP contributes to memory loss and early phase of pathogenesis of Alzheimer disease PMID: 19263040
31. The results demonstrate that ET-1 induces CPR production in VSMCs via ET(A) receptor followed by ROS and MAPK signal pathway. PMID: 19748488

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KEGG: rno:25419

STRING: 10116.ENSRNOP00000000058

UniGene: Rn.16463