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中文名稱：小鼠雌二醇(E2)酶聯免疫試劑盒
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貨號：CSB-E05109m
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規格：96T/48T
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價格：￥3200/￥2500
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其他：
產品詳情
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產品描述：小鼠雌二醇(E2)酶聯免疫試劑盒（CSB-E05109m）為競爭法ELISA試劑盒，定量檢測血清、血漿樣本中的E2含量。雌二醇（E2）是小鼠體內重要的雌激素，負責調節女性特征、附屬性器官成熟和月經-排卵周期，促進乳腺導管系統產生。研究顯示，E2在促進小鼠肺腺癌進展中起關鍵作用，其機制可能與E2受體ERβ信號通路相關，而IL-6可能通過下調ERβ信號通路抑制E2促進肺腺癌進展。試劑盒檢測范圍為50 pg/ml-1200 pg/ml，靈敏度為40 pg/ml。適用于基礎科研場景，例如探究生殖周期中激素動態變化、評估藥物或環境因素對內分泌系統的影響，或用于代謝性疾病模型中激素水平與病理進程的關聯性分析本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
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別名：N/A
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縮寫：E2
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種屬：Mus musculus (Mouse)
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樣本類型：serum, plasma
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檢測范圍：50 pg/ml-1200 pg/ml.
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靈敏度：40 pg/ml.
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反應時間：1-5h
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樣本體積：50-100ul
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檢測波長：450 nm
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研究領域：Signal Transduction
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測定原理：quantitative
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測定方法：Competitive
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精密度：
Intra-assay Precision (Precision within an assay): CV%<15%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<15%
Three samples of known concentration were tested in twenty assays to assess.
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標準曲線：
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
pg/ml
OD1
OD2
Average
0
2.185
2.254
2.220
50
1.176
1.167
1.172
120
0.743
0.718
0.730
250
0.518
0.529
0.524
500
0.340
0.321
0.331
1200
0.177
0.168
0.172
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數據處理：
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貨期：3-5 working days
引用文獻
- A genetically engineered mouse model for ovarian hyperstimulation syndrome W Bi, X Jin, S Wu, J Wang, X Su, L Gao, Z He,PeerJ,2025
- Decreased protein activator of interferon induced protein kinase (PRKRA) involved in menopause-related cholesterol metabolic disorders by regulating cholesterol biosynthesis L Xu, J Xu, W Shi, S Zhang, T Guo, S Zou,Lipids in Health and Disease,2025
- Afamin Ameliorates Testosterone Propionate (TP)-Induced Oxidative Stress and Mitochondrial Damage in Human Ovarian Granulosa Tumor Cells (KGN) by Upregulating the Expression of SIRT1 YL Ma, ZW Li, Z Wang, AJ Yang,Molecular Biology,2024
- Circulating Interleukin-6 Mediates PM2.5-Induced Ovarian Injury by Suppressing the PPARγ Pathway Y Chen, J Zhang, T Zhang, Y Wu, Y Xi, T Wu, M Li, Y Li,Research,2024
- Mesenchymal stem cell-derived extracellular vesicles therapy for primary ovarian insufficiency: a systematic review and meta-analysis of pre-clinical studies SR Firouzabadi, I Mohammadi, K Ghafourian,Journal of Ovarian Research,2024
- High-fat diet-induced L-saccharopine accumulation inhibits estradiol synthesis and damages oocyte quality by disturbing mitochondrial homeostasis J Wen, Y Feng, L Xue, S Yuan, Q Chen, A Luo,Gut Microbes,2024
- DCAF2 is essential for the development of uterine epithelia and mouse fertility M Yang, K Wang, L Zhang, H Zhang,Frontiers in Cell and Developmental Biology,2024
- Integrated Single-Cell and Spatial Transcriptomics Reveal Microenvironment Disruptions by Androgen in Mouse Ovary M Luo, X Yang, M Zhou, J Zhang, B Yu, H Lian, J Ye,iScience,2024
- The effect of norepinephrine on ovarian dysfunction by mediating ferroptosis in mice model hanqing hong, C Xiao, lichun Weng, Q Wang, D Lai,bioRxiv,2024
- Mesenchymal stem cell-derived apoptotic vesicles ameliorate impaired ovarian folliculogenesis in polycystic ovary syndrome and ovarian aging by targeting WNT signaling Y Fu,Theranostics,2024
- Spatiotemporal transcriptomic changes of human ovarian aging and the regulatory role of FOXP1 M Wu,Nature aging,2024
- Preserving Fertility: Minimizing Ovarian Lymphatic Drainage Disruption in Gynecological Cancer Surgeries D Chen,/,2024
- Rfamide-Related Peptide-3 (RFRP-3) Receptor Gene is Expressed in Mouse Ovarian Granulosa Cells: Potential Role of RFRP-3 in Steroidogenesis and Apoptosis X Guo,/,2023
- Ovary-derived Decellularized Extracellular Matrix-based Bioink for Fabricating 3D Primary Ovarian Cells-laden Structures for Mouse Ovarian Failure Correction J Zheng,International Journal of Bioprinting,2023
- Preventive effect of swim bladder hydrolysates on cyclophosphamide‐induced ovarian injury in mice E Ge,journal of obstetrics and gynaecology research,2023
- The Effects of Paeonia lactiflora Pall. and Astragalus Membranaceus Single Extracts on Bone Metabolic Profile in Ovariectomized Mice H Liu,/,2024
- Vomeronasal Receptors Associated with Circulating Estrogen Processing Chemosensory Cues in Semi-Aquatic Mammals W Xie,International journal of molecular sciences,2023
- Gestational cadmium exposure disrupts fetal liver development via repressing estrogen biosynthesis in placental trophoblasts YT Fu,Food and chemical toxicology,2023
- Human Pluripotent Stem Cell–Mesenchymal Stem Cell-Derived Exosomes Promote Ovarian Granulosa Cell Proliferation and Attenuate Cell Apoptosis Induced by Cyclophosphamide in a POI-like Mouse Model L Zhang,Molecules,2023
- Increased cellular senescence in doxorubicin-induced murine ovarian injury: effect of senolytics Y Gao,GeroScience,2023
- The Effect of an Extract and Fractions of Date Pits on Some Plasma Constituents, Reproductive Hormones, and Testicular Histology in Male Mice M Al Za'abi,The Scientific World Journal,2022
- Ahi1 regulates serotonin production by the GR/ERβ/TPH2 pathway involving sexual differences in depressive behaviors B Wang,Cell communication and signaling,2022
- Senotherapy Protects against Cisplatin-Induced Ovarian Injury by Removing Senescent Cells and Alleviating DNA Damage D Du,Oxidative medicine and cellular longevity,2022
- Anti-Müllerian Hormone Inhibits FSH-Induced Cumulus Oocyte Complex In Vitro Maturation and Cumulus Expansion in Mice X Yu,Animals,2022
- A Docosahexaenoic Acid Derivative (N-Benzyl Docosahexaenamide) as a Potential Therapeutic Candidate for Treatment of Ovarian Injury in the Mouse Model L Guo,Molecules,2022
- Estrogen signaling regulates seasonal changes of the prostate in wild ground squirrels (Spermophilus dauricus) H Zhang,The Journal of steroid biochemistry and molecular biology,2022
- Cyanidin-3-O-glucoside ameliorates cadmium induced uterine epithelium proliferation in mice Dacheng Yang,Journal of Hazardous Materials,2021
- Overaccumulation of fat caused rapid reproductive senescence but not loss of ovarian reserve in ob/ob mice ML Mollah,Journal of the Endocrine Society,2020
- Synergistic effect of Huyang Yangkun Formula and embryonic stem cells on 4-vinylcyclohexene diepoxide induced premature ovarian insufficiency in mice M Li,Chinese Medicine,2020
- Potential of Auraptene in Improvement of Oocyte Maturation, Fertilization Rate, and Inflammation in Polycystic Ovary Syndrome Mouse Model M Abizadeh,Reproductive Sciences,2020
- Receptor Binding Inhibitor Suppresses Carcinogenesis of Cervical Cancer by Depressing Levels of FSHR and ERβ in Mice Gong Z,Anti-Cancer Agents in Medicinal Chemistry,2019
- Hashimoto’s thyroiditis impairs embryo implantation by compromising endometrial morphology and receptivity markers in euthyroid mice Wu Z, et al,Reproductive Biology and Endocrinology,2019
- Therapeutic effects of human umbilical cord mesenchymal stem cell-derived microvesicles on premature ovarian insufficiency in mice Z Yang, et al,Stem Cell Research & Therapy,2019
- FSH receptor binding inhibitor restrains ovarian cancer through down-regulating expression levels of FSHR and ERβ in mice Zhuandi G, et al,Gene,2018
- Determine the Role of FSH Receptor Binding Inhibitor in Regulating Ovarian Follicles Development and Expression of FSHR and ERα in Mice Luju Lai.et al,BioMed Research International,2018
- In vivo toxicity and genotoxicity of beauvericin and enniatins. Combined approach to study in vivo toxicity and genotoxicity of mycotoxins beauvericin (BEA) and enniatin B (ENNB) Francesca Maranghi.et al,EFSA Journal,2018
- FSH receptor binding inhibitor restrains follicular development and possibly attenuates carcinogenesis of ovarian cancer through down-regulating expression levels of FSHR and ERβ in normal ovarian tissues GongZhuandi.et al,Gene,2018
- Silica nanoparticle exposure inducing granulosa cell apoptosis and follicular atresia in female Balb/c mice Liu J.et al,Environ Sci Pollut Res Int,2017
- Methoxsalen supplementation attenuates bone loss and inflammatory response in ovariectomized mice. Ham JR.et al,Chem Biol Interact.,2017
- Bu Shen Tiao Chong recipe restores diminished ovary reserve through the BDNF pathway. Xia T.et al,J Assist Reprod Genet.,2016
- Sex hormone affects the severity of non-alcoholic steatohepatitis through the MyD88-dependent IL-6 signaling pathway Xin G et al,Exp Biol Med (Maywood),2015
產品評價
平均分:
樣品類型：血清
樣品信息：小鼠
稀釋比：其他 稀釋五倍
產品評價： 標曲不用自己配這一點很方便，實驗結果兩次基本趨勢相同，標曲較好
By 李老師
樣品類型：血清
樣品信息：小鼠
稀釋比：沒有稀釋
產品評價： 我用CSB-L05109m檢測正常血清性激素E2水平，標準曲線的OD值為1.7585-0.2015，樣品OD值為0.804-1.423，標曲R值0.99837，操作簡單，方便實驗新手進行檢測。
By 鄭老師
相關產品
靶點詳情
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最新研究進展：stradiol（E2）是一種雌激素，是雌性動物體內最主要的雌激素之一。E2在女性中起著重要的生殖和生理功能，如卵巢發育、月經周期、性腺功能等。E2的最新研究顯示，它與許多疾病的發生和發展有關，包括乳腺癌、子宮內膜癌、骨質疏松、自身免疫病等。目前已有很多研究致力于研究E2的生物學功能和在疾病治療方面的應用。
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