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中文名稱：小鼠花生四烯酸(AA)酶聯(lián)免疫試劑盒
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貨號：CSB-E14102m
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規(guī)格：96T/48T
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價格：￥3200/￥2500
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其他：
產(chǎn)品詳情
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產(chǎn)品描述：小鼠花生四烯酸(AA)酶聯(lián)免疫試劑盒（CSB-E14102m）為競爭法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的AA含量。花生四烯酸（AA）是小鼠體內(nèi)一種必需脂肪酸，其代謝主要通過環(huán)氧化酶（COX）和脂氧合酶（LOX）兩條途徑，產(chǎn)物包括前列腺素和白三烯等炎癥介質(zhì)。研究表明，AA代謝產(chǎn)物與胰腺癌等腫瘤的發(fā)生發(fā)展密切相關(guān)，成為潛在的治療靶點。試劑盒檢測范圍為15.625 ng/mL-1000 ng/mL，靈敏度為13.797 ng/mL。通過特異性抗體與樣本中AA的高效結(jié)合，可精準(zhǔn)定量生物樣本中AA的濃度變化，為研究炎癥反應(yīng)機制、脂質(zhì)代謝調(diào)控、心血管疾病模型或藥物干預(yù)效果提供可靠工具，尤其適用于小鼠模型中與AA通路相關(guān)的神經(jīng)退行性疾病、代謝綜合征等基礎(chǔ)科研領(lǐng)域的數(shù)據(jù)獲取。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
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別名：N/A
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縮寫：AA
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種屬：Mus musculus (Mouse)
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樣本類型：serum, plasma, tissue homogenates
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檢測范圍：15.625 ng/mL-1000 ng/mL
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靈敏度：13.797 ng/mL
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反應(yīng)時間：1-5h
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樣本體積：50-100ul
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檢測波長：450 nm
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研究領(lǐng)域：Biochemicals
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測定原理：quantitative
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測定方法：Competitive
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精密度：
Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<10%
Three samples of known concentration were tested in twenty assays to assess.
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線性度：
To assess the linearity of the assay, samples were spiked with high concentrations of Mouse AA in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
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標(biāo)準(zhǔn)曲線：
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
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數(shù)據(jù)處理：
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貨期：3-5 working days
引用文獻
- Expression Pattern of ALOXE3 in Mouse Brain Suggests Its Relationship with Seizure Susceptibility HL Tang,Cellular and Molecular Neurobiology,2020
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相關(guān)問答
I want to know if the HRP-AA reagent in EKC31383 also containing in BSA with TBS solution? Moreover, Arachidonic acid is directly conjugated to HRP?
Mouse Arachidonic Acid(AA) ELISA KitCSB-E14102m
This kit is based on competitive method. There is a reagent in the kit named HRP-AA（This is concentrated HRP-conjugate，and diluent is also provided together).Pls let me know if you have any further questions. Thank you.
靶點詳情
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最新研究進展：近年來，研究人員的關(guān)注重點已經(jīng)逐漸轉(zhuǎn)向了花生四烯酸（Arachidonic Acid，AA）的作用機制、與疾病的關(guān)系以及調(diào)節(jié)方法等方面。最新的研究表明，花生四烯酸代謝異常與多種疾病的發(fā)生和發(fā)展密切相關(guān)。例如，心血管疾病和腫瘤的發(fā)生與發(fā)展與花生四烯酸的代謝異常有一定關(guān)系。在炎癥過程中，花生四烯酸代謝產(chǎn)物可以促進炎癥介質(zhì)的生成，從而導(dǎo)致血管損傷、炎癥反應(yīng)和血栓形成等。在腫瘤發(fā)生和發(fā)展過程中，花生四烯酸代謝產(chǎn)物也可以促進腫瘤細胞增殖、侵襲和轉(zhuǎn)移，并在腫瘤血管生成過程中發(fā)揮一定作用。因此，研究人員正在探索通過調(diào)節(jié)花生四烯酸代謝途徑，減少炎癥介質(zhì)的生成以及抑制腫瘤細胞生長和擴散等方法，以實現(xiàn)對疾病的預(yù)防和治療。
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