Monkey Interleukin-1 alpha (IL1A) ELISA kit

產(chǎn)品詳情

文獻引用 (1) 說明書下載

Intra-assay Precision (Precision within an assay): CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<10%

Three samples of known concentration were tested in twenty assays to assess.

產(chǎn)品描述：

猴白介素1a(IL1A)酶聯(lián)免疫試劑盒（CSB-E10041Mo）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的IL1A含量。IL1A即白細胞介素 1α，在炎癥、免疫反應(yīng)等生理過程中扮演重要角色。諸多研究聚焦其釋放機制，它可啟動炎癥信號通路，刺激免疫細胞活化和細胞因子產(chǎn)生。探索其背景和機制，有助于開發(fā)針對IL1A的治療方法，為相關(guān)疾病治療帶來新思路。試劑盒檢測范圍為7.8 pg/mL-500 pg/mL，適用于探索靈長類動物模型中IL1A的生物學(xué)功能、炎癥相關(guān)疾病機制研究，或評估藥物干預(yù)、基因修飾對IL - 1信號通路的影響，為免疫學(xué)、病理學(xué)及藥理學(xué)領(lǐng)域的體外實驗提供可靠工具。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
別名：

IL1A ELISA Kit; Interleukin-1 alpha ELISA Kit; IL-1 alpha ELISA Kit; Hematopoietin-1 ELISA Kit
縮寫：

IL1A
Uniprot No.：

P48089
種屬：

Monkey
樣本類型：

serum, plasma, tissue homogenates
檢測范圍：

7.8 pg/mL-500 pg/mL
靈敏度：

1.95 pg/mL
反應(yīng)時間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領(lǐng)域：

Immunology
測定原理：

quantitative
測定方法：

Sandwich

精密度：

標準曲線：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

功能：

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
亞細胞定位：

Cytoplasm. Secreted.
蛋白家族：

IL-1 family
數(shù)據(jù)庫鏈接：

KEGG: mcc:700193

STRING: 9544.ENSMMUP00000026006

UniGene: Mmu.3361