Human WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 2(WFIKKN2) ELISA kit
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中文名稱：人WAP，kazal，免疫球蛋白，kunitz和NTR結(jié)構(gòu)域蛋白2(WFIKKN2)酶聯(lián)免疫試劑盒
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貨號(hào)：CSB-EL026099HU
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規(guī)格：96T/48T
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價(jià)格：￥3600/￥2500
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其他：
產(chǎn)品詳情
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產(chǎn)品描述：人WAP，kazal，免疫球蛋白，kunitz和NTR結(jié)構(gòu)域蛋白2(WFIKKN2)酶聯(lián)免疫試劑盒（CSB-EL026099HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的WFIKKN2含量。WFIKKN2是一種新的TGF-β家族成員的胞外結(jié)合蛋白，高表達(dá)于卵巢和睪丸，與TGF-β家族成員如MSTN、GDF11、TGF-β1、BMP2和BMP4等結(jié)合，通過調(diào)節(jié)這些因子的功能來正向或負(fù)向調(diào)控生殖細(xì)胞發(fā)生。其具體作用機(jī)制涉及阻斷SMAD信號(hào)通路，激活非經(jīng)典途徑，以及與生殖細(xì)胞發(fā)育相關(guān)。試劑盒檢測范圍為31.25 pg/mL-2000 pg/mL，靈敏度為7.81 pg/mL。適用于細(xì)胞生物學(xué)、分子病理學(xué)等科研領(lǐng)域，可應(yīng)用于炎癥相關(guān)疾病模型、腫瘤微環(huán)境研究或發(fā)育生物學(xué)中WFIKKN2蛋白表達(dá)動(dòng)態(tài)監(jiān)測，為探索其分子功能提供可靠工具。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
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別名：WFIKKN2 ELISA Kit; GASP1 ELISA Kit; WFIKKNRP ELISA Kit; UNQ9235/PRO31996 ELISA Kit; WAP ELISA Kit; Kazal ELISA Kit; immunoglobulin ELISA Kit; Kunitz and NTR domain-containing protein 2 ELISA Kit; Growth and differentiation factor-associated serum protein 1 ELISA Kit; GASP-1 ELISA Kit; hGASP-1 ELISA Kit; WAP ELISA Kit; follistatin ELISA Kit; immunoglobulin ELISA Kit; Kunitz and NTR domain-containing-related protein ELISA Kit; WFIKKN-related protein ELISA Kit
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縮寫：WFIKKN2
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Uniprot No.：
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種屬：Homo sapiens (Human)
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樣本類型：serum, plasma, tissue homogenates
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檢測范圍：31.25 pg/mL-2000 pg/mL
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靈敏度：7.8 pg/mL
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反應(yīng)時(shí)間：1-5h
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樣本體積：50-100ul
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檢測波長：450 nm
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研究領(lǐng)域：Cell Biology
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測定原理：quantitative
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測定方法：Sandwich
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數(shù)據(jù)處理：
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貨期：3-5 working days
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin.
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基因功能參考文獻(xiàn)：
- WFIKKN2 expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
- After eccentric exercise, postmenopausal women not using hormone therapy (HT) expressed higher levels of GASP-1 while postmenopausal women using HT showed a significant increased expression over controls. PMID: 22395277
- Creatine supplementation in conjunction with resistance training lead to greater decreases in serum myostatin (p<0.05), but had not additional effect on GASP-1 (p>0.05). PMID: 20026378
- Newly discovered WFIKKNPR gene structure and tissue distribution of gene expression is commpared with that of the WFIKKN gene in adult and fetal tissues and organs PMID: 11928817
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亞細(xì)胞定位：Secreted.
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蛋白家族：WFIKKN family
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組織特異性：Primarily expressed in ovary, testis and brain, but not in liver. In fetal tissues, it is primarily expressed in brain, skeletal muscle, thymus and kidney.
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數(shù)據(jù)庫鏈接：
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