Human Oligodendrocyte-myelin glycoprotein(OMG) ELISA kit

產品詳情

文獻引用 (1) 說明書下載

Intra-assay Precision (Precision within an assay): CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<10%

Three samples of known concentration were tested in twenty assays to assess.

產品描述：

人少突細胞髓磷脂糖蛋白(OMG)酶聯免疫試劑盒（CSB-EL016334HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的OMG含量。試劑盒檢測范圍為0.156 ng/mL-10 ng/mL，適用于神經科學基礎研究，如多發性硬化癥、腦白質營養不良等疾病模型的分子機制探索，亦可應用于藥物開發中髓鞘修復相關化合物的體外效果評價。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
別名：

Oligodendrocyte-myelin glycoprotein ELISA Kit; Omg ELISA Kit; OMGP ELISA Kit; OMGP_HUMAN ELISA Kit
縮寫：

OMG
Uniprot No.：

P23515
種屬：

Homo sapiens (Human)
樣本類型：

serum, plasma, tissue homogenates
檢測范圍：

0.156 ng/mL-10 ng/mL
靈敏度：

0.039 ng/mL
反應時間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領域：

Neuroscience
測定原理：

quantitative
測定方法：

Sandwich

精密度：

線性度：

To assess the linearity of the assay, samples were spiked with high concentrations of human OMG in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
	Sample	Serum(n=4)
1:1	Average %	85
	Range %	80-89
1:2	Average %	97
	Range %	92-102
1:4	Average %	92
	Range %	87-98
1:8	Average %	98
	Range %	94-102

回收率：

The recovery of human OMG spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.

Sample Type	Average % Recovery	Range
Serum (n=5)	88	84-92
EDTA plasma (n=4)	107	102-112

標準曲線：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

METHODS FOR DIFFERENTIATING ISCHEMIC STROKE FROM HEMORRHAGIC STROKE Montaner Viallonga, Joan.et al,United States Patent Application ,2017

功能：

Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.
基因功能參考文獻：
1. The results do not support a relationship between the OMGP gene and the learning disability phenotype observed in neurofibromatosis type 1. PMID: 21534343
2. novel mutations and novel polymorphisms in coding regions and 5'UTR were detected in patients with with non-syndromic mental retardation PMID: 16425041
3. Data show that oligodendrocyte-myelin glycoprotein is downregulated in schizophrenia anterior temporal lobe revealed by shotgun proteome analysis. PMID: 19034380
亞細胞定位：

Cell membrane; Lipid-anchor, GPI-anchor.
組織特異性：

Oligodendrocytes and myelin of the central nervous system.
數據庫鏈接：

HGNC: 8135

OMIM: 164345

KEGG: hsa:4974

STRING: 9606.ENSP00000247271

UniGene: Hs.113874