Recombinant Mouse C-C motif chemokine 9 protein (Ccl9)
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中文名稱:Recombinant Mouse C-C motif chemokine 9 protein(Ccl9) (Active)
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品名簡稱:Recombinant Mouse Ccl9 protein (Active)
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貨號:CSB-AP001281MO
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說明書:
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規格:¥852
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圖片:
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其他:
產品詳情
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純度:>95% as determined by SDS-PAGE.
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內毒素:Less than 1.0 EU/μg as determined by LAL method.
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生物活性:Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration range of 0.1-10 ng/ml.
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基因名:Ccl9
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Uniprot No.:
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別名:CCF18; Ccl9; CCL9(31-101); CCL9_MOUSE; Chemokine CC motif ligand 9; Macrophage inflammatory protein 1-gamma; Macrophage inflammatory protein-related protein 2; MIP-1-gamma; MRP-2; SCYA10; SCYA9; Small inducible cytokine A9; Small-inducible cytokine A9
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種屬:Mus musculus (Mouse)
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蛋白長度:Full Length of Mature Protein
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來源:E.Coli
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分子量:11.6 kDa
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表達區域:22-122aa
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氨基酸序列QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q
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蛋白標簽:Tag-Free
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產品提供形式:Liquid or Lyophilized powder
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緩沖液:0.2 μm filtered PBS, pH 7.4 ,lyophilized
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儲存條件:Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保質期:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期:5-10 business days
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Datasheet & COA:Please contact us to get it.
相關產品
靶點詳情
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功能:Monokine with inflammatory, pyrogenic and chemokinetic properties. Circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors.
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基因功能參考文獻:
- CCL9 secreted by splenic macrophages induces a CCR1dependent accumulation of MDSCs. PMID: 30365155
- Results show that MIP-1g promotes tumor cell growth in vitro through the activation of NFkB pathway in colorectal tumor cells. PMID: 28108624
- we report that chemokine CCL9 was highly induced in Gr-1(+)CD11b(+) immature myeloid cells and in premetastatic lung in tumor-bearing mice PMID: 26483204
- Plasmid codelivery of murine CCL19 and CCL28 enhanced Ag-specific systemic and mucosal Ab responses to HIV-1 gp140, augmented balanced Th1/Th2 responses, and increased lymphocyte subsets in various lymphoid tissues. PMID: 23858028
- There is protein-DNA interaction between ETV5 and Ccl9, suggesting that ETV5 might be a direct regulator of Ccl9 expression. PMID: 20799334
- Results reveal the potential involvement of CCL9 and CCR1 in macrophage and microglial cells by CpG-ODNs and may help understanding the role of the chemokine/chemokine receptor pairs in macrophage/microglia under physiologic and pathologic conditions. PMID: 19883904
- MRP-2 may be an important contributing factor in the development of atherosclerosis PMID: 12173416
- CCL9 and its receptor CCR1 are the major chemokine and receptor species expressed by osteoclasts, CCL9 has a role in the regulation of bone resorption PMID: 12397598
- An important role for CCL9 is demonstrated in the recruitment of CD11b+ dendritic cells to the dome regions of mouse Peyer's patches. PMID: 12960300
- MIP-1 gamma plays an important role in the differentiation & survival of osteoclasts, & bone resorption, most likely via an autocrine pathway. PMID: 15265944
- Keratinocyte-derived chemokine (KC) and MIP-2 alpha differ in their mediation of neutrophil function (apoptosis and chemotaxis) and contribution to the pathogenesis of lung injury following hemorrhage subsequent to sepsis. PMID: 15961314
- BCR/ABL repressed CCL9 expression at the transcriptional level PMID: 17160016
- involved in calcium mobilization and chemotaxis PMID: 11500837
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亞細胞定位:Secreted.
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蛋白家族:Intercrine beta (chemokine CC) family
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組織特異性:Expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain.
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