YWHAG

YWHAG，全稱為酪氨酸3-單加氧酶/色氨酸5-單加氧酶激活蛋白γ，常見別名包括14-3-3GAMMA、14-3-3 gamma和PPP1R170。該蛋白屬于14-3-3蛋白家族，通過與含磷酸絲氨酸的蛋白結(jié)合來介導(dǎo)信號轉(zhuǎn)導(dǎo)，在細胞內(nèi)穩(wěn)態(tài)和信號調(diào)控中發(fā)揮重要作用。YWHAG蛋白參與多種細胞過程，包括細胞周期調(diào)控、凋亡和應(yīng)激反應(yīng)。研究表明，YWHAG蛋白與阿爾茨海默病等神經(jīng)退行性疾病密切相關(guān)，其水平變化可作為疾病診斷和預(yù)后的生物標志物。近年來，針對YWHAG蛋白的藥物研發(fā)取得進展，例如開發(fā)基于YWHAG蛋白的ELISA試劑盒用于疾病檢測，以及探索其作為潛在治療靶點的藥物設(shè)計。此外，YWHAG蛋白在腫瘤、自身免疫性疾病等領(lǐng)域的病理機制也受到關(guān)注，為相關(guān)疾病的治療提供了新的思路。

熱銷產(chǎn)品

YWHAG Recombinant Monoclonal Antibody (CSB-RA824302A0HU)

驗證數(shù)據(jù)

Western Blot
Positive WB detected in: Hela whole cell lysate, Jurkat whole cell lysate, A549 whole cell lysate, K562 whole cell lysate
All lanes: YWHAG antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 29 kDa
Observed band size: 29 kDa

IHC image of CSB-RA824302A0HU diluted at 1:100 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.

YWHAG Antibody (CSB-PA026288LA01HU)

驗證數(shù)據(jù)

Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA026288LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA026288LA01HU at dilution of 1:100

Western Blot
Positive WB detected in: Mouse brain tissue, A431 whole cell lysate, Human placenta tissue
All lanes: YWHAG antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 29 kDa
Observed band size: 29 kDa

Western Blot
Positive WB detected in: Hela whole cell lysate, Jurkat whole cell lysate, NIH/3T3 whole cell lysate, U251 whole cell lysate, K562 whole cell lysate, Rat brain tissue
All lanes: YWHAG antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 29 kDa
Observed band size: 29 kDa

Immunoprecipitating YWHAG in NIH/3T3 whole cell lysate
Lane 1: Rabbit control IgG instead of CSB-PA026288LA01HU in NIH/3T3 whole cell lysate.For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
Lane 2: CSB-PA026288LA01HU (5μg) + NIH/3T3 whole cell lysate (500μg)
Lane 3: NIH/3T3 whole cell lysate (20μg)

Western Blot
Positive WB detected in: Mouse Brain tissue lysate,Rat Brain tissue lysate,NIH/3T3 whole cell lysate, Rat Lung tissue lysate,Mouse Lung tissue lysate,Rat Liver tissue lysate,Rat Kidney tissue lysate,Mouse Kidney tissue lysate
All lanes: YWHAG antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 28.3 kDa
Observed band size: 28kDa

Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA026288LA01HU at dilution of 1:100

Human 14-3-3 protein gamma(YWHAG) ELISA kit (CSB-EL026288HU)

驗證數(shù)據(jù)

貨號：CSB-EL026288HU

規(guī)格：96T/48T

靈敏度：0.156 ng/mL

檢測范圍：0.625 ng/mL-40 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

YWHAG Antibody

YWHAG Protein

YWHAG ELISA Kit

YWHAG Antibodies

YWHAG for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA026288GA01HU	YWHAG Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA948368	YWHAG Antibody	Human,Mouse,Rat	ELISA,WB,IHC,IF
CSB-PA060090	YWHAG Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA066436	YWHAG Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA589658	YWHAG Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA026288LA01HU	YWHAG Antibody	Human, Mouse, Rat	ELISA, WB, IHC, IP
CSB-PA026288LB01HU	YWHAG Antibody, HRP conjugated	Human	ELISA
CSB-PA026288LD01HU	YWHAG Antibody, Biotin conjugated	Human	ELISA
CSB-RA824302A0HU	YWHAG Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC

YWHAG Proteins

YWHAG Proteins for Ovis aries (Sheep)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP026288SH CSB-EP026288SH CSB-BP026288SH CSB-MP026288SH CSB-EP026288SH-B	Recombinant Sheep 14-3-3 protein gamma (YWHAG)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

YWHAG Proteins for Bos taurus (Bovine)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP026288BO CSB-EP026288BO CSB-BP026288BO CSB-MP026288BO CSB-EP026288BO-B	Recombinant Bovine 14-3-3 protein gamma (YWHAG)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

YWHAG Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP026288MO CSB-EP026288MO CSB-BP026288MO CSB-MP026288MO CSB-EP026288MO-B	Recombinant Mouse 14-3-3 protein gamma (Ywhag)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

YWHAG Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP026288HU CSB-EP026288HU CSB-BP026288HU CSB-MP026288HU CSB-EP026288HU-B	Recombinant Human 14-3-3 protein gamma (YWHAG)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

YWHAG Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP026288RA CSB-EP026288RA CSB-BP026288RA CSB-MP026288RA CSB-EP026288RA-B	Recombinant Rat 14-3-3 protein gamma (Ywhag)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

YWHAG Proteins for Gallus gallus (Chicken)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP704881CH CSB-EP704881CH CSB-BP704881CH CSB-MP704881CH CSB-EP704881CH-B	Recombinant Chicken 14-3-3 protein gamma (YWHAG)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

YWHAG Proteins for Pongo abelii (Sumatran orangutan)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP712963PYX CSB-EP712963PYX CSB-BP712963PYX CSB-MP712963PYX CSB-EP712963PYX-B	Recombinant Pongo abelii 14-3-3 protein gamma (YWHAG)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli