VPS18
VPS18，別名PEP3，在多種組織中廣泛表達，尤其在骨髓、腎臟等組織中表達量較高。VPS18的作用機制涉及其作為CORVET和HOPS復合體的核心亞基，這兩個復合體參與介導內膜運輸過程，特別是與晚期內體/溶酶體相關，可能介導內體/溶酶體途徑中的囊泡運輸步驟。VPS18對于維持細胞內蛋白質的正確分選和運輸至關重要，其功能異常可能與某些遺傳性疾病相關，如Hermansky-Pudlak綜合征。VPS18還參與調控神經細胞存活、遷移和樹突發育等重要生理功能，對于研究人類神經退行性疾病的診斷和防治新策略提供了新的理論依據和思路。
熱銷產品
VPS18 Antibody (CSB-PA882173LA01HU)
驗證數據
IHC image of CSB-PA882173LA01HU diluted at 1:300 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
VPS18 Antibodies
VPS18 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA025895GA01HU | VPS18 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA882173LA01HU | VPS18 Antibody | Human | ELISA, IHC |
| CSB-PA882173LB01HU | VPS18 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA882173LC01HU | VPS18 Antibody, FITC conjugated | Human | |
| CSB-PA882173LD01HU | VPS18 Antibody, Biotin conjugated | Human | ELISA |
VPS18 Proteins
VPS18 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP882173HU CSB-EP882173HU CSB-BP882173HU CSB-MP882173HU CSB-EP882173HU-B |
Recombinant Human Vacuolar protein sorting-associated protein 18 homolog (VPS18), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
