VEGFB
VEGFB，全稱為血管內皮生長因子B，是VEGF家族的重要成員之一，主要與血管內皮生長因子受體-1（VEGFR-1）和神經纖毛蛋白1（NRP-1）結合。VEGFB蛋白在多種組織和器官中表達，其常見別名包括血管滲透因子（VPF），最初是從牛的垂體濾泡星狀細胞的條件培養基中純化出來的。VEGFB蛋白在組織細胞分化成熟過程中發揮著重要作用，與肝臟疾病的發生、進展和結局密切相關。研究表明，VEGFB蛋白能夠促進肝細胞再生，抑制慢性乙型肝炎、肝硬化的發展，并在腫瘤的診斷與治療、肝臟移植的排斥反應等方面發揮重要作用。此外，VEGFB蛋白還在心肌梗死、心力衰竭或神經退行性病變等組織退化/死亡的條件下，通過其促血管生成/存活作用，維持正常血管密度和通透性。目前，針對VEGFB蛋白的藥物研發主要集中在眼科疾病和肝臟疾病領域，例如，有研究將VEGFB蛋白應用于預防和治療急性前葡萄膜炎，取得了良好的效果。隨著對VEGFB蛋白作用機制的深入研究，其在疾病治療中的應用前景將更加廣闊。
熱銷產品
Recombinant Human Vascular endothelial growth factor B (VEGFB) (CSB-EP025834HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
VEGFB Antibody (CSB-PA025834LA01HU)
驗證數據
Western Blot
Positive WB detected in: Rat heart tissue, Rat spleen tissue, Mouse heart tissue, Mouse liver tissue, Mouse kidney tissue, Mouse brain tissue
All lanes: VEGFB antibody at 3.5μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 22 kDa
Observed band size: 28 kDa
Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA025834LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA025834LA01HU at dilution of 1:100
Human Vascular Endothelial cell Growth Factor B,VEGF-B ELISA KIT (CSB-E04758h)
驗證數據
貨號：CSB-E04758h
規格：96T/48T
靈敏度：3.9 pg/mL
檢測范圍：15.6 pg/mL-1000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
VEGFB Antibodies
VEGFB for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA959480 | VEGFB Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA004444 | VEGFB Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA005891 | VEGFB Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA025834LA01HU | VEGFB Antibody | Human, Mouse, Rat | ELISA, WB, IHC |
| CSB-PA025834LB01HU | VEGFB Antibody, HRP conjugated | Human | ELISA |
| CSB-PA025834LC01HU | VEGFB Antibody, FITC conjugated | Human | |
| CSB-PA025834LD01HU | VEGFB Antibody, Biotin conjugated | Human | ELISA |
VEGFB Proteins
VEGFB Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025834MO CSB-EP025834MO CSB-BP025834MO CSB-MP025834MO CSB-EP025834MO-B |
Recombinant Mouse Vascular endothelial growth factor B (Vegfb) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VEGFB Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025834HU | Recombinant Human Vascular endothelial growth factor B (VEGFB) | Yeast |
| CSB-BP025834HU CSB-MP025834HU CSB-EP025834HU-B |
Recombinant Human Vascular endothelial growth factor B (VEGFB) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP025834HU | Recombinant Human Vascular endothelial growth factor B (VEGFB) | E.coli |
| CSB-EP025834HU1 | Recombinant Human Vascular endothelial growth factor B (VEGFB), partial | E.coli |
| CSB-EP025834HU1a2 | Recombinant Human Vascular endothelial growth factor B (VEGFB), partial | E.coli |
| CSB-EP025834HU1a0 | Recombinant Human Vascular endothelial growth factor B (VEGFB), partial | E.coli |
VEGFB Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025834RA CSB-EP025834RA CSB-BP025834RA CSB-MP025834RA CSB-EP025834RA-B |
Recombinant Rat Vascular endothelial growth factor B (Vegfb) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VEGFB Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025834BO CSB-EP025834BO CSB-BP025834BO CSB-MP025834BO CSB-EP025834BO-B |
Recombinant Bovine Vascular endothelial growth factor B (VEGFB) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
VEGFB ELISA Kit
VEGFB ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04758h | Human Vascular Endothelial cell Growth Factor B,VEGF-B ELISA KIT | serum, plasma, tissue homogenates | 3.9 pg/mL |
VEGFB ELISA Kit for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E07365m | Mouse Vascular Endothelial cell Growth Factor B,VEGF-B ELISA kit | serum, plasma, cell culture supernates, tissue homogenates | 0.195 pg/mL |
