SOD1
SOD1，即銅鋅超氧化物歧化酶（Cu/Zn superoxide dismutase），是一種具有關鍵抗氧化功能的酶，其結構特征在于含有銅和鋅離子輔基。功能上，SOD1通過催化超氧陰離子歧化為氧氣和過氧化氫，維持細胞內活性氧的平衡，從而保護細胞免受氧化應激損傷。在信號通路方面，SOD1通過調節胞內活性氧水平，影響細胞信號轉導過程，包括激活NF-κB、AP-1以及JAK-STAT等信號通路，這些通路與細胞增殖、凋亡和炎癥反應等密切相關。此外，SOD1的異常表達與神經系統疾病如肌萎縮側索硬化癥（ALS）的發病過程緊密相關。
熱銷產品
SOD1 Recombinant Monoclonal Antibody
驗證數據
Positive WB detected in: 293 whole cell lysate, Hela whole cell lysate, Jurkat whole cell lysate, MCF-7 whole cell lysate, K562 whole cell lysate, HepG2 whole cell lysate, U87 whole cell lysate
All lanes: SOD1 antibody at 1:1500
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 16 kDa
Observed band size: 18 kDa
Overlay histogram showing Jurkat cells stained with CSB-RA829583A0HU (red line) at 1:50. The cells were fixed with 70% Ethylalcohol (18h) and then incubated in 10% normal goat serum to block non-specific protein-protein interactions followedby the antibody (1μg/1*106 cells) for 1 h at 4℃.The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 30min at 4℃. Control antibody (green line) was Rabbit IgG (1μg/1*106 cells) used under the same conditions. Acquisition of >10,000 events was performed.
SOD1 Antibodies
SOD1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA02864D0Rb | SOD1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA02864B0Rb | SOD1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA022397GA01HU | SOD1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA02864C0Rb | SOD1 Antibody, FITC conjugated | Human | |
| CSB-PA02864A0Rb | SOD1 Antibody | Human, Mouse | ELISA, WB, IHC, IF |
| CSB-PA004131 | SOD1 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA080200 | SOD1 Antibody | Human,Mouse,Rat | WB, IHC |
| CSB-PA238446 | SOD1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-RA829583A0HU | SOD1 Recombinant Monoclonal Antibody | Human | ELISA, WB, FC |
| CSB-RA022397MA1HU | SOD1 Recombinant Monoclonal Antibody | Human | ELISA, IF, FC |
SOD1 Proteins
SOD1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP022397HU CSB-EP022397HU CSB-BP022397HU CSB-MP022397HU CSB-EP022397HU-B |
Recombinant Human Superoxide dismutase [Cu-Zn] (SOD1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP000121HU | Recombinant Human Superoxide dismutase [Cu-Zn] (SOD1) (Active) | E.Coli |
| CSB-AP000131HU | Recombinant Human Superoxide dismutase [Cu-Zn] protein (SOD1) | E.Coli |
SOD1 ELISA Kit
SOD1 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E16845h | Human Superoxide dismutase [Cu-Zn] (SOD1) ELISA kit | serum, plasma, tissue homogenates | 15.6 pg/ml |
