SETD7
Histone-lysine N-methyltransferase SETD7 is a protein in humans that is encoded by SETD7 gene. Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.
SETD7 Antibodies
SETD7 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA995563 | SETD7 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA093769 | SETD7 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA840975LA01HU | SETD7 Antibody | Human | ELISA, WB, IHC |
SETD7 Proteins
SETD7 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP700117XBF CSB-EP700117XBF CSB-BP700117XBF CSB-MP700117XBF CSB-EP700117XBF-B |
Recombinant Xenopus tropicalis Histone-lysine N-methyltransferase SETD7 (setd7) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SETD7 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP735311DIL CSB-EP735311DIL CSB-BP735311DIL CSB-MP735311DIL CSB-EP735311DIL-B |
Recombinant Danio rerio Histone-lysine N-methyltransferase SETD7 (setd7) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SETD7 Proteins for Halocynthia roretzi (Sea squirt)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP767185HTQ CSB-EP767185HTQ CSB-BP767185HTQ CSB-MP767185HTQ CSB-EP767185HTQ-B |
Recombinant Halocynthia roretzi Histone-lysine N-methyltransferase SETD7 (setd7) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SETD7 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP840975HU CSB-EP840975HU CSB-BP840975HU CSB-MP840975HU CSB-EP840975HU-B |
Recombinant Human Histone-lysine N-methyltransferase SETD7 (SETD7) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP840975HU1 | Recombinant Human Histone-lysine N-methyltransferase SETD7 (SETD7),Partial | E.coli |
SETD7 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP845030MO CSB-EP845030MO CSB-BP845030MO CSB-MP845030MO CSB-EP845030MO-B |
Recombinant Mouse Histone-lysine N-methyltransferase SETD7 (Setd7) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
