SCN10A
SCN10A,別名PN3、peripheral nerve sodium channel 3等。它是由人類SCN10A基因編碼的蛋白質,位于3號染色體上。SCN10A的作用機制是通過形成電壓門控鈉通道,調節鈉離子的流動,特別是在痛覺信號的傳遞和心臟電生理活動中發揮作用。SCN10A在神經細胞如背根神經節的nociceptors中表達,參與疼痛信號的傳遞;在心臟中,SCN10A可能參與心律的調節,其變異與心臟傳導障礙如Brugada綜合征有關。SCN10A的突變或異常表達與多種疼痛障礙、心律失常等疾病相關,是研究和治療這些疾病的潛在靶點。
熱銷產品
SCN10A Antibody (CSB-PA750910LA01HU)
驗證數據

Immunofluorescence staining of SH-SY5Y cells with CSB-PA750910LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
SCN10A Antibodies
SCN10A for Homo sapiens (Human)
產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
---|---|---|---|
CSB-PA251062 | SCN10A Antibody | Human | ELISA,IHC |
CSB-PA146616 | SCN10A Antibody | Human | ELISA,IHC |
CSB-PA750910LA01HU | SCN10A Antibody | Human | ELISA, IF |
CSB-PA750910LB01HU | SCN10A Antibody, HRP conjugated | Human | ELISA |
CSB-PA750910LC01HU | SCN10A Antibody, FITC conjugated | Human | |
CSB-PA750910LD01HU | SCN10A Antibody, Biotin conjugated | Human | ELISA |