PDGFRB
PDGFRB，即血小板衍生生長因子受體β，別名IBGC4、IMF1、JTK12、PDGF R beta、PDGFR 1。它是一種由PDGFRB基因編碼的跨膜受體酪氨酸激酶，主要在多種組織中表達，尤其在腎臟、肺和消化系統中。PDGFRB的作用機制主要是通過與其配體血小板衍生生長因子結合，激活下游的信號傳導途徑，如PI3K/AKT和RAS/RAF/MEK/ERK等，從而調控細胞的增殖、分化、遷移和存活。PDGFRB在生物學上的意義非常廣泛，它參與了多種生理過程的調節，包括血管生成、器官發育和傷口愈合等。PDGFRB的功能異常與多種疾病有關，如某些類型的癌癥和血管疾病，因此，它是藥物開發和疾病治療中的一個潛在靶點。
熱銷產品
Recombinant Human Platelet-derived growth factor receptor beta (PDGFRB), partial (CSB-EP017713HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
PDGFRB Recombinant Monoclonal Antibody (CSB-RA213932A0HU)
驗證數據
IHC image of CSB-RA213932A0HU diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
PDGFRB Antibodies
PDGFRB for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA017713GA01HU | PDGFRB Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA828739 | PDGFRB (Ab-751) Antibody | Human,Rat | ELISA,WB |
| CSB-PA979025 | Phospho-PDGFRB (Tyr740) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA556830 | PDGFRB (Ab-771) Antibody | Human,Rat | ELISA,WB |
| CSB-PA000745 | Phospho-PDGFRB (Y1021) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA003726 | PDGFRB Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA004625 | PDGFRB Antibody | Human,Rat | WB, ELISA |
| CSB-PA030005 | Phospho-PDGFRB (Y771) Antibody | Human,Rat | WB, ELISA |
| CSB-PA030006 | Phospho-PDGFRB (Y740) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA030007 | Phospho-PDGFRB (Y751) Antibody | Human,Mouse,Rat | IHC, IF, ELISA |
| CSB-PA030008 | PDGFRB Antibody | Human,Mouse,Rat | IHC, IF, ELISA |
| CSB-PA030009 | PDGFRB Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA030010 | PDGFRB Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA208206 | PDGFRB Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA266610 | PDGFRB Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA017713LA01HU | PDGFRB Antibody | Human | ELISA, IHC, IF |
| CSB-PA017713LD01HU | PDGFRB Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA017713LC01HU | PDGFRB Antibody, FITC conjugated | Human | |
| CSB-PA017713LB01HU | PDGFRB Antibody, HRP conjugated | Human | ELISA |
| CSB-RA017713A740phHU | Phospho-PDGFRB (Y740) Recombinant Monoclonal Antibody | Human | ELISA, WB |
| CSB-RA213932A0HU | PDGFRB Recombinant Monoclonal Antibody | Human | ELISA, IHC |
PDGFRB Proteins
PDGFRB Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP017713MO CSB-EP017713MO CSB-BP017713MO CSB-MP017713MO CSB-EP017713MO-B |
Recombinant Mouse Platelet-derived growth factor receptor beta (Pdgfrb), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PDGFRB Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP017713HU CSB-BP017713HU CSB-MP017713HU CSB-EP017713HU-B |
Recombinant Human Platelet-derived growth factor receptor beta (PDGFRB), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP017713HU | Recombinant Human Platelet-derived growth factor receptor beta (PDGFRB), partial | E.coli |
PDGFRB Proteins for Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP304446TKY CSB-EP304446TKY CSB-BP304446TKY CSB-MP304446TKY CSB-EP304446TKY-B |
Recombinant Takifugu rubripes Platelet-derived growth factor receptor beta (pdgfrb), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PDGFRB Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP764838DO CSB-EP764838DO CSB-BP764838DO CSB-MP764838DO CSB-EP764838DO-B |
Recombinant Dog Platelet-derived growth factor receptor beta (PDGFRB), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PDGFRB ELISA Kit
PDGFRB ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL017713HU | Human Beta-type platelet-derived growth factor receptor(PDGFRB) ELISA kit | serum, plasma, tissue homogenates | 15.6 pg/mL |
PDGFRB ELISA Kit for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL017713MO | Mouse Beta-type platelet-derived growth factor receptor(PDGFRB) ELISA kit |
