PCCA
PCCA全稱為丙酰輔酶A羧化酶α亞基,也被稱為丙酰輔酶A羧化酶α鏈。該蛋白是丙酰輔酶A羧化酶復合物的重要組成部分,該復合物在丙酸代謝中發揮關鍵作用。PCCA蛋白的缺陷會導致丙酸血癥,這是一種罕見的遺傳代謝疾病。目前,針對丙酸血癥的治療主要依賴于肝移植,而mRNA療法如mRNA-3927的研發為治療該疾病提供了新的希望。此外,PCCA蛋白的研究也為開發針對其他代謝性疾病的藥物提供了潛在靶點。
熱銷產品
Recombinant Human Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCA) (CSB-EP017522HU)
驗證數據

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
PCCA Antibody (CSB-PA017522LA01HU)
驗證數據

Western Blot
Positive WB detected in: NIH/3T3 whole cell lysate, Hela whole cell lysate
All lanes: PCCA antibody at 4µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 81, 78, 76 kDa
Observed band size: 81 kDa

Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA017522LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA017522LA01HU at dilution of 1:100
PCCA Antibodies
PCCA for Homo sapiens (Human)
產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
---|---|---|---|
CSB-PA017522LA01HU | PCCA Antibody | Human, Mouse | ELISA, WB, IHC |
CSB-PA017522LB01HU | PCCA Antibody, HRP conjugated | Human | ELISA |
CSB-PA017522LC01HU | PCCA Antibody, FITC conjugated | Human | |
CSB-PA017522LD01HU | PCCA Antibody, Biotin conjugated | Human | ELISA |
PCCA Proteins
PCCA Proteins for Homo sapiens (Human)
產品貨號 | 產品名稱 | 來源 |
---|---|---|
CSB-YP017522HU CSB-BP017522HU CSB-MP017522HU CSB-EP017522HU-B |
Recombinant Human Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCA) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP017522HU | Recombinant Human Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCA) | E.coli |