OSM
OSM（Oncostatin M）是一種細(xì)胞因子蛋白。它是白細(xì)胞介素6（Interleukin-6，IL-6）家族中的成員之一，其結(jié)構(gòu)是一種由單一多肽鏈組成的蛋白質(zhì)，它與細(xì)胞表面上的受體結(jié)合，觸發(fā)下游信號(hào)轉(zhuǎn)導(dǎo)途徑。 OSM在免疫調(diào)節(jié)、細(xì)胞增殖、分化和炎癥等生理過程中發(fā)揮著重要作用。參與調(diào)控多種細(xì)胞類型的增殖和分化，包括肝細(xì)胞、胚胎干細(xì)胞、神經(jīng)細(xì)胞等。在炎癥性疾病中，OSM可以調(diào)節(jié)免疫細(xì)胞的活化和炎癥反應(yīng)。在腫瘤發(fā)展中，OSM可能促進(jìn)腫瘤細(xì)胞的增殖和侵襲。 由于OSM在生理和病理過程中的重要作用，對(duì)其的研究對(duì)于理解免疫調(diào)節(jié)、炎癥反應(yīng)和腫瘤生物學(xué)等方面具有重要意義。同時(shí)，OSM也被認(rèn)為是潛在的治療靶點(diǎn)，針對(duì)OSM和其受體的治療方法可能有助于調(diào)節(jié)疾病過程和發(fā)展新的治療策略。
更多相關(guān)閱讀：抑瘤素M (OSM): 白介素IL-6細(xì)胞因子家族成員，腫瘤、骨代謝、慢性炎癥性等疾病的潛力靶點(diǎn)？
熱銷產(chǎn)品
● OSM Recombinant Monoclonal Antibody CSB-RA017260MA1HU
驗(yàn)證數(shù)據(jù)
The Binding Activity of Human OSM with Anti-OSM Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human OSM (CSB-MP017260HU1) at 2 μg/mL can bind Anti-OSM recombinant antibody, the EC50 is 3.048-3.860 ng/mL
● Recombinant Human Oncostatin-M(OSM),partial (Active) CSB-MP017260HU1
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human OSM at 2μg/mL can bind Anti-OSM recombinant antibody (CSB-RA017260MA1HU)，the EC50 is 3.048-3.860 ng/mL.
OSM Antibodies
OSM for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA09694A0Rb | OSM Antibody | Human | ELISA, IHC |
| CSB-PA09694C0Rb | OSM Antibody, FITC conjugated | Human | |
| CSB-PA09694B0Rb | OSM Antibody, HRP conjugated | Human | ELISA |
| CSB-PA244255 | OSM Antibody | Human | ELISA,WB,IHC |
| CSB-PA934414 | OSM Antibody | Human | ELISA,IHC |
| CSB-RA017260MA1HU | OSM Recombinant Monoclonal Antibody | Human | ELISA |
OSM for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA723970LA01RA | Osm Antibody | Rat | ELISA, IF |
| CSB-PA723970LB01RA | Osm Antibody, HRP conjugated | Rat | ELISA |
| CSB-PA723970LC01RA | Osm Antibody, FITC conjugated | Rat |
OSM Proteins
OSM Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP017260HU CSB-EP017260HU CSB-BP017260HU CSB-MP017260HU CSB-EP017260HU-B |
Recombinant Human Oncostatin-M (OSM), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP017260HU2 | Recombinant Human Oncostatin-M (OSM), partial | E.coli |
| CSB-AP002231HU | Recombinant Human Oncostatin-M protein (OSM), partial (Active) | E.Coli |
| CSB-AP002241HU | Recombinant Human Oncostatin-M protein (OSM), partial (Active) | E.Coli |
| CSB-AP002251HU | Recombinant Human Oncostatin-M protein (OSM), partial (Active) | E.Coli |
| CSB-EP017260HU1 | Recombinant Human Oncostatin-M (OSM) | E.coli |
| CSB-YP017260HUc7 | Recombinant Human Oncostatin-M (OSM), partial | Yeast |
| CSB-MP017260HU1 | Recombinant Human Oncostatin-M (OSM), partial (Active) | Mammalian cell |
| CSB-MP017260HU1d9 | Recombinant Human Oncostatin-M (OSM), partial | Mammalian cell |
| CSB-MP017260HU-WD | Recombinant Human Oncostatin-M (OSM) (Active) | Mammalian cell |
OSM Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP017260BO CSB-EP017260BO CSB-BP017260BO CSB-MP017260BO CSB-EP017260BO-B |
Recombinant Bovine Oncostatin-M (OSM) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
OSM Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP017260MO CSB-EP017260MO CSB-BP017260MO CSB-MP017260MO CSB-EP017260MO-B |
Recombinant Mouse Oncostatin-M (Osm) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
OSM Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP723970RA | Recombinant Rat Oncostatin-M (Osm) | Yeast |
| CSB-EP723970RA CSB-BP723970RA CSB-EP723970RA-B |
Recombinant Rat Oncostatin-M (Osm) | E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP723970RA | Recombinant Rat Oncostatin-M (Osm) | Mammalian cell |
| CSB-EP723970RAb0 | Recombinant Rat Oncostatin-M (Osm) | E.coli |
OSM ELISA Kit
OSM ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04696h | Human Oncostatin-M,OSM ELISA KIT | serum, plasma, cell culture supernates | 1.56 pg/mL |
OSM ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04697m | Mouse Oncostatin-M,OSM ELISA KIT | serum, plasma, cell culture supernates, tissue homogenates | 0.78 pg/mL |
OSM ELISA Kit for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E07402r | Rat oncostatin M (OSM) ELISA kit | serum, plasma | 3.9 pg/mL |
