NEIL3
Endonuclease 8-like 3 is a protein in humans that is encoded by NEIL3 gene. DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.
NEIL3 Antibodies
NEIL3 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA015695GA01HU | NEIL3 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA065468 | NEIL3 Antibody | Human | ELISA,WB |
| CSB-PA003396 | NEIL3 Antibody | Human,Mouse | WB, IHC, ELISA |
NEIL3 Proteins
NEIL3 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP662133BO CSB-EP662133BO CSB-BP662133BO CSB-MP662133BO CSB-EP662133BO-B |
Recombinant Bovine Endonuclease 8-like 3 (NEIL3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NEIL3 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP809085MO CSB-EP809085MO CSB-BP809085MO CSB-MP809085MO CSB-EP809085MO-B |
Recombinant Mouse Endonuclease 8-like 3 (Neil3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NEIL3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP855036HU CSB-EP855036HU CSB-BP855036HU CSB-MP855036HU CSB-EP855036HU-B |
Recombinant Human Endonuclease 8-like 3 (NEIL3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
