NEDD4L
E3 ubiquitin-protein ligase NEDD4-like is a protein in humans that is encoded by NEDD4L gene. E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, KCNH2, EAAT1 or CLC5.
NEDD4L Antibodies
NEDD4L for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA015682GA01HU | NEDD4L Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA680788 | NEDD4L Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA978449 | NEDD4L Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA850411LA01HU | NEDD4L Antibody | Human | ELISA, WB, IF |
| CSB-PA850411LB01HU | NEDD4L Antibody, HRP conjugated | Human | ELISA |
| CSB-PA850411LC01HU | NEDD4L Antibody, FITC conjugated | Human | |
| CSB-PA850411LD01HU | NEDD4L Antibody, Biotin conjugated | Human | ELISA |
NEDD4L Proteins
NEDD4L Proteins for Pongo abelii (Sumatran orangutan)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP732737PYX CSB-EP732737PYX CSB-BP732737PYX CSB-MP732737PYX CSB-EP732737PYX-B |
Recombinant Pongo abelii E3 ubiquitin-protein ligase NEDD4-like (NEDD4L), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NEDD4L Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP804501MO CSB-EP804501MO CSB-BP804501MO CSB-MP804501MO CSB-EP804501MO-B |
Recombinant Mouse E3 ubiquitin-protein ligase NEDD4-like (Nedd4l), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NEDD4L Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP850411HU CSB-EP850411HU CSB-BP850411HU CSB-MP850411HU CSB-EP850411HU-B |
Recombinant Human E3 ubiquitin-protein ligase NEDD4-like (NEDD4L), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP850411HU(A4) | Recombinant Human E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) | E.coli |
