MTOR

MTOR，即哺乳動物雷帕霉素靶蛋白，別名哺乳動物靶蛋白、Rapamycin受體、FRAP等。它是一種多功能的絲氨酸/蘇氨酸蛋白激酶，由人體細(xì)胞自身的基因編碼。MTOR是雷帕霉素(mTOR)信號通路的關(guān)鍵調(diào)控因子，主要在細(xì)胞內(nèi)參與調(diào)控蛋白質(zhì)合成、細(xì)胞增殖、代謝和自噬等過程。MTOR的作用機制涉及到其作為兩個不同的復(fù)合體mTORC1和mTORC2的催化亞基，這兩個復(fù)合體在細(xì)胞內(nèi)響應(yīng)不同的營養(yǎng)和環(huán)境信號，調(diào)節(jié)不同的生物學(xué)過程。MTOR在生物學(xué)上的意義非常廣泛，它參與了多種細(xì)胞生命活動的調(diào)控。作為細(xì)胞內(nèi)營養(yǎng)和能量狀態(tài)的主要感受器，MTOR通過整合多種信號，如氨基酸、生長因子和能量狀態(tài)等，來調(diào)節(jié)細(xì)胞的生長和代謝。mTORC1的活性與細(xì)胞的蛋白質(zhì)合成、自噬和細(xì)胞大小調(diào)控密切相關(guān)，而mTORC2則參與細(xì)胞的生存和細(xì)胞骨架的組織。MTOR信號通路的異常激活與多種疾病有關(guān)，包括癌癥、糖尿病、心血管疾病和神經(jīng)退行性疾病等，因此，MTOR抑制劑已成為治療這些疾病的潛在藥物。

熱銷產(chǎn)品

MTOR Antibody (CSB-PA008968HA01HU)

驗證數(shù)據(jù)

Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA008968HA01HU at dilution of 1:100

Immunofluorescent analysis of Hela cells using CSB-PA008968HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

MTOR Antibody

MTOR Protein

MTOR ELISA Kit

MTOR Antibodies

MTOR for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA008968GA01HU	MTOR Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA271384	Phospho-MTOR (Ser2448) Antibody	Human,Mouse,Rat	ELISA,WB,IHC,IF
CSB-PA208208	MTOR (Ab-2448) Antibody	Human,Mouse,Rat	ELISA,WB,IHC,IF
CSB-PA054657	MTOR (Ab-2481) Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA000576	Phospho-MTOR (S2448) Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA000652	Phospho-MTOR (T2446) Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA003333	MTOR Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA008479	Phospho-MTOR (S2481) Antibody	Human,Mouse,Rat	IHC, IF, ELISA
CSB-PA008481	MTOR Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA876444	MTOR Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA273227	MTOR Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA008968HA01HU	MTOR Antibody	Human	ELISA, IHC, IF
CSB-PA008968HB01HU	MTOR Antibody, HRP conjugated	Human	ELISA
CSB-PA008968HC01HU	MTOR Antibody, FITC conjugated	Human
CSB-PA008968HD01HU	MTOR Antibody, Biotin conjugated	Human	ELISA
CSB-RA008968A2481phHU	Phospho-MTOR (S2481) Recombinant Monoclonal Antibody	Human	ELISA, WB, IF
CSB-RA008968A2448phHU	Phospho-MTOR (S2448) Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC, IF

MTOR Proteins

MTOR Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP008968HU CSB-BP008968HU CSB-MP008968HU CSB-EP008968HU-B	Recombinant Human Serine/threonine-protein kinase mTOR (MTOR), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP008968HU	Recombinant Human Serine/threonine-protein kinase mTOR (MTOR), partial	E.coli

MTOR Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP008968RA CSB-EP008968RA CSB-BP008968RA CSB-MP008968RA CSB-EP008968RA-B	Recombinant Rat Serine/threonine-protein kinase mTOR (Mtor), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MTOR Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP881349MO CSB-EP881349MO CSB-BP881349MO CSB-MP881349MO CSB-EP881349MO-B	Recombinant Mouse Serine/threonine-protein kinase mTOR (Mtor)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli