MSH6
DNA mismatch repair protein Msh6 is a protein in humans that is encoded by MSH6 gene. Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch.
MSH6 Antibodies
MSH6 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA015032GA01HU | MSH6 Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-MA0150321A0m | MSH6 Monoclonal Antibody | Human | ELISA,IHC |
| CSB-PA015032HA01HU | MSH6 Antibody | Human | ELISA, IHC, IF |
| CSB-PA015032HD01HU | MSH6 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA125723 | MSH6 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA002850 | MSH6 Antibody | Human,Mouse,Monkey | WB, IHC, IF, ELISA |
| CSB-PA051370 | MSH6 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA589405 | MSH6 Antibody | Human,Mouse | ELISA,WB,IHC |
MSH6 Proteins
MSH6 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015032HU CSB-BP015032HU CSB-MP015032HU CSB-EP015032HU-B |
Recombinant Human DNA mismatch repair protein Msh6 (MSH6), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP015032HU | Recombinant Human DNA mismatch repair protein Msh6 (MSH6), partial | E.coli |
MSH6 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015032MO CSB-EP015032MO CSB-BP015032MO CSB-MP015032MO CSB-EP015032MO-B |
Recombinant Mouse DNA mismatch repair protein Msh6 (Msh6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MSH6 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015032SXV CSB-EP015032SXV CSB-BP015032SXV CSB-MP015032SXV CSB-EP015032SXV-B |
Recombinant Schizosaccharomyces pombe DNA mismatch repair protein msh6 (msh6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MSH6 Proteins for Arabidopsis thaliana (Mouse-ear cress)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP519077DOA CSB-EP519077DOA CSB-BP519077DOA CSB-MP519077DOA CSB-EP519077DOA-B |
Recombinant Arabidopsis thaliana DNA mismatch repair protein MSH6 (MSH6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MSH6 Proteins for Dictyostelium discoideum (Slime mold)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP690881DKK CSB-EP690881DKK CSB-BP690881DKK CSB-MP690881DKK CSB-EP690881DKK-B |
Recombinant Dictyostelium discoideum DNA mismatch repair protein Msh6 (msh6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MSH6 Proteins for Drosophila melanogaster (Fruit fly)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP894276DLU CSB-EP894276DLU CSB-BP894276DLU CSB-MP894276DLU CSB-EP894276DLU-B |
Recombinant Drosophila melanogaster Probable DNA mismatch repair protein Msh6 (Msh6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
