MAPK8
Mitogen-activated protein kinase 8 is a protein in humans that is encoded by MAPK8 gene. Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK8/JNK1. In turn, MAPK8/JNK1 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. Phosphorylates the replication licensing factor CDT1, inhibiting the interaction between CDT1 and the histone H4 acetylase HBO1 to replication origins.
MAPK8 Antibodies
MAPK8 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA013466GA01HU | MAPK8 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA222139 | MAPK8 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA236755 | MAPK8 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA176985 | MAPK8 Antibody | Human,Rat | ELISA,WB,IHC |
| CSB-PA282702 | MAPK8 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA16759A0Rb | MAPK8 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA16759B0Rb | MAPK8 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA16759D0Rb | MAPK8 Antibody, Biotin conjugated | Human | ELISA |
MAPK8 Proteins
MAPK8 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP013466HU CSB-EP013466HU CSB-MP013466HU CSB-EP013466HU-B |
Recombinant Human Mitogen-activated protein kinase 8 (MAPK8) | Yeast E.coli Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-BP013466HU | Recombinant Human Mitogen-activated protein kinase 8 (MAPK8), partial | Baculovirus |
| CSB-BP013466HUb1 | Recombinant Human Mitogen-activated protein kinase 8 (MAPK8), partial | Baculovirus |
MAPK8 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP013466RA CSB-EP013466RA CSB-BP013466RA CSB-MP013466RA CSB-EP013466RA-B |
Recombinant Rat Mitogen-activated protein kinase 8 (Mapk8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAPK8 Proteins for Xenopus laevis (African clawed frog)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP013466XBE CSB-EP013466XBE CSB-BP013466XBE CSB-MP013466XBE CSB-EP013466XBE-B |
Recombinant Xenopus laevis Mitogen-activated protein kinase 8 (mapk8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAPK8 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP013466MO CSB-EP013466MO CSB-BP013466MO CSB-MP013466MO CSB-EP013466MO-B |
Recombinant Mouse Mitogen-activated protein kinase 8 (Mapk8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAPK8 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP013466DIL CSB-EP013466DIL CSB-BP013466DIL CSB-MP013466DIL CSB-EP013466DIL-B |
Recombinant Danio rerio Mitogen-activated protein kinase 8 (mapk8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
